"G-Quadruplexes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)
| Descriptor ID |
D054856
|
| MeSH Number(s) |
G02.111.570.820.486.550 G05.360.580.550
|
| Concept/Terms |
G-Quadruplexes- G-Quadruplexes
- G Quadruplexes
- Guanine-Quadruplexes
- Guanine Quadruplexes
Guanine-Tetrads- Guanine-Tetrads
- Guanine Tetrads
- Guanine-Tetrad
- Guanine-Quartets
- Guanine Quartets
- Guanine-Quartet
G-Quadruplexes, DNA- G-Quadruplexes, DNA
- G Quadruplexes, DNA
- Tetraplex DNA
- DNA, Tetraplex
- DNA G-Quadruplexes
- DNA G Quadruplexes
- DNA, Quadruplex
- Quadruplex DNA
G-Quadruplexes, RNA- G-Quadruplexes, RNA
- G Quadruplexes, RNA
- RNA G-Quadruplexes
- RNA, G-Quadruplexes
- G-Quadruplexes RNA
- G-Quadruplexes RNAs
- RNA, G Quadruplexes
- RNAs, G-Quadruplexes
|
Below are MeSH descriptors whose meaning is more general than "G-Quadruplexes".
Below are MeSH descriptors whose meaning is more specific than "G-Quadruplexes".
This graph shows the total number of publications written about "G-Quadruplexes" by people in this website by year, and whether "G-Quadruplexes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2017 | 3 | 3 | 6 |
| 2018 | 4 | 1 | 5 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "G-Quadruplexes" by people in Profiles.
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Selective Binding and Redox-Activity on Parallel G-Quadruplexes by Pegylated Naphthalene Diimide-Copper Complexes. Molecules. 2021 Aug 19; 26(16).
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Detecting and Profiling Endogenous RNA G-Quadruplexes in the Human Transcriptome. Int J Mol Sci. 2021 Jul 27; 22(15).
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SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction. Nucleic Acids Res. 2021 07 21; 49(13):7695-7712.
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A Rolling Circle-Amplified G-Quadruplex/Hemin DNAzyme for Chemiluminescence Immunoassay of the SARS-CoV-2 Protein. Anal Chem. 2021 07 20; 93(28):9933-9938.
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Potential G-quadruplexes and i-Motifs in the SARS-CoV-2. PLoS One. 2021; 16(6):e0250654.
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Discovery of G-quadruplex-forming sequences in SARS-CoV-2. Brief Bioinform. 2021 03 22; 22(2):1150-1160.
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Ribavirin shows antiviral activity against SARS-CoV-2 and downregulates the activity of TMPRSS2 and the expression of ACE2 in vitro. Can J Physiol Pharmacol. 2021 May; 99(5):449-460.
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CNBP Binds and Unfolds In Vitro G-Quadruplexes Formed in the SARS-CoV-2 Positive and Negative Genome Strands. Int J Mol Sci. 2021 Mar 05; 22(5).
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Targeting RNA G-Quadruplex in SARS-CoV-2: A Promising Therapeutic Target for COVID-19? Angew Chem Int Ed Engl. 2021 01 04; 60(1):432-438.
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G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection. Biosens Bioelectron. 2020 Nov 01; 167:112494.