"RNA, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA consisting of two strands as opposed to the more prevalent single-stranded RNA. Most of the double-stranded segments are formed from transcription of DNA by intramolecular base-pairing of inverted complementary sequences separated by a single-stranded loop. Some double-stranded segments of RNA are normal in all organisms.
| Descriptor ID |
D012330
|
| MeSH Number(s) |
D13.444.735.490 G02.111.570.820.486.775 G05.360.580.775
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "RNA, Double-Stranded".
Below are MeSH descriptors whose meaning is more specific than "RNA, Double-Stranded".
This graph shows the total number of publications written about "RNA, Double-Stranded" by people in this website by year, and whether "RNA, Double-Stranded" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 5 | 3 | 8 |
| 2018 | 6 | 7 | 13 |
| 2019 | 3 | 1 | 4 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 4 | 5 |
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Below are the most recent publications written about "RNA, Double-Stranded" by people in Profiles.
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An isoform of Dicer protects mammalian stem cells against multiple RNA viruses. Science. 2021 07 09; 373(6551):231-236.
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A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19. Mol Ther. 2021 07 07; 29(7):2219-2226.
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COVID-19 and hypertension: Is there a role for dsRNA and activation of Toll-like receptor 3? Vascul Pharmacol. 2021 10; 140:106861.
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Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age. Brain Behav Immun. 2021 07; 95:413-428.
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SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes. Proc Natl Acad Sci U S A. 2021 04 20; 118(16).
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Cutting Edge: Reduced Adenosine-to-Inosine Editing of Endogenous Alu RNAs in Severe COVID-19 Disease. J Immunol. 2021 04 15; 206(8):1691-1696.
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The role of A-to-I RNA editing in infections by RNA viruses: Possible implications for SARS-CoV-2 infection. Clin Immunol. 2021 05; 226:108699.
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MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells. Cell Rep. 2021 01 12; 34(2):108628.
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The Inhaled Steroid Ciclesonide Blocks SARS-CoV-2 RNA Replication by Targeting the Viral Replication-Transcription Complex in Cultured Cells. J Virol. 2020 12 09; 95(1).
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COVID-19: a user's guide, status of the art and an original proposal to terminate viral recurrence. Minerva Med. 2021 Feb; 112(1):144-152.