"Toll-Like Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
| Descriptor ID |
D051193
|
| MeSH Number(s) |
D12.776.543.750.705.910.500
|
| Concept/Terms |
Toll-Like Receptors- Toll-Like Receptors
- Toll Like Receptors
- Toll-Like Receptor
- Receptor, Toll-Like
- Toll Like Receptor
- Receptors, Toll-Like
- Receptors, Toll Like
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptors".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptors".
This graph shows the total number of publications written about "Toll-Like Receptors" by people in this website by year, and whether "Toll-Like Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2006 | 3 | 0 | 3 |
| 2007 | 3 | 1 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 3 | 3 |
| 2017 | 15 | 12 | 27 |
| 2018 | 13 | 15 | 28 |
| 2019 | 8 | 7 | 15 |
| 2020 | 0 | 2 | 2 |
| 2021 | 2 | 6 | 8 |
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Below are the most recent publications written about "Toll-Like Receptors" by people in Profiles.
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DAMPening COVID-19 Severity by Attenuating Danger Signals. Front Immunol. 2021; 12:720192.
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Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19. Nat Commun. 2021 08 11; 12(1):4869.
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SARS-CoV-2 Infected Pediatric Cerebral Cortical Neurons: Transcriptomic Analysis and Potential Role of Toll-like Receptors in Pathogenesis. Int J Mol Sci. 2021 Jul 28; 22(15).
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Ultraviolet radiation, vitamin D, and COVID-19. Ital J Dermatol Venerol. 2021 Jun; 156(3):366-373.
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Natural killer cells play an important role in virus infection control: Antiviral mechanism, subset expansion and clinical application. Clin Immunol. 2021 06; 227:108727.
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Interindividual immunogenic variants: Susceptibility to coronavirus, respiratory syncytial virus and influenza virus. Rev Med Virol. 2021 11; 31(6):e2234.
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Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody. Front Immunol. 2021; 12:650331.
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Increased TLR/MyD88 signaling in patients with obesity: is there a link to COVID-19 disease severity? Int J Obes (Lond). 2021 05; 45(5):1152-1154.
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Platelets and viruses. Platelets. 2021 Apr 03; 32(3):325-330.
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Innate Receptor Activation Patterns Involving TLR and NLR Synergisms in COVID-19, ALI/ARDS and Sepsis Cytokine Storms: A Review and Model Making Novel Predictions and Therapeutic Suggestions. Int J Mol Sci. 2021 Feb 20; 22(4).