Ikaros Transcription Factor
"Ikaros Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that plays a role as a key regulator of HEMATOPOIESIS. Aberrant Ikaros expression has been associated with LYMPHOBLASTIC LEUKEMIA.
| Descriptor ID |
D051740
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| MeSH Number(s) |
D12.776.260.522.500 D12.776.930.375.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ikaros Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Ikaros Transcription Factor".
This graph shows the total number of publications written about "Ikaros Transcription Factor" by people in this website by year, and whether "Ikaros Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 3 | 3 |
| 2018 | 3 | 1 | 4 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Ikaros Transcription Factor" by people in Profiles.
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Terminal Effector CD8 T Cells Defined by an IKZF2+IL-7R- Transcriptional Signature Express Fc?RIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity. J Immunol. 2019 10 15; 203(8):2210-2221.
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Overexpression of CD49d in trisomy 12 chronic lymphocytic leukemia patients is mediated by IRF4 through induction of IKAROS. Leukemia. 2019 05; 33(5):1278-1302.
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Intensified treatment for IKZF1-deleted childhood leukaemia. Lancet Oncol. 2018 09; 19(9):e441.
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Baicalein Inhibits Proliferation of Myeloma U266 Cells by Downregulating IKZF1 and IKZF3. Med Sci Monit. 2018 May 05; 24:2809-2817.
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IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia. J Clin Oncol. 2018 04 20; 36(12):1240-1249.
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Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells. Front Immunol. 2018; 9:19.
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Hepatocyte Growth Factor Improves the Therapeutic Efficacy of Human Bone Marrow Mesenchymal Stem Cells via RAD51. Mol Ther. 2018 03 07; 26(3):845-859.
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Copy number profiling of adult relapsed B-cell precursor acute lymphoblastic leukemia reveals potential leukemia progression mechanisms. Genes Chromosomes Cancer. 2017 11; 56(11):810-820.
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Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription. J Exp Med. 2017 Jul 03; 214(7):2059-2071.