Kruppel-Like Transcription Factors
"Kruppel-Like Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of zinc finger transcription factors that share homology with Kruppel protein, Drosophila. They contain a highly conserved seven amino acid spacer sequence in between their ZINC FINGER MOTIFS.
| Descriptor ID |
D051741
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| MeSH Number(s) |
D12.776.260.522 D12.776.930.375
|
| Concept/Terms |
Kruppel-Like Transcription Factors- Kruppel-Like Transcription Factors
- Kruppel Like Transcription Factors
- Transcription Factors, Kruppel-Like
- Kruppel-Like Factors
- Kruppel Like Factors
|
Below are MeSH descriptors whose meaning is more general than "Kruppel-Like Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Kruppel-Like Transcription Factors".
This graph shows the total number of publications written about "Kruppel-Like Transcription Factors" by people in this website by year, and whether "Kruppel-Like Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 3 | 3 |
| 2017 | 11 | 4 | 15 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 2 | 3 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kruppel-Like Transcription Factors" by people in Profiles.
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SARS-CoV-2 Infection Is Associated with Reduced Krüppel-like Factor 2 in Human Lung Autopsy. Am J Respir Cell Mol Biol. 2021 08; 65(2):222-226.
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The zinc finger transcription factor, KLF2, protects against COVID-19 associated endothelial dysfunction. Signal Transduct Target Ther. 2021 07 12; 6(1):266.
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Identification of the SARS-CoV-2 Entry Receptor ACE2 as a Direct Target for Transcriptional Repression by Miz1. Front Immunol. 2021; 12:648815.
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ceRNA analysis of SARS-CoV-2. Arch Virol. 2021 Jan; 166(1):271-274.
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Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice. Sci Adv. 2020 08; 6(33):eabb7238.
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Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development. Cell Stem Cell. 2019 Nov 07; 25(5):697-712.e6.
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A comparative study on different stemness gene expression between dental pulp stem cells vs. dental bud stem cells. Eur Rev Med Pharmacol Sci. 2019 Feb; 23(4):1626-1633.
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Kr?ppel-like factors (KLFs) in renal physiology and disease. EBioMedicine. 2019 Feb; 40:743-750.
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Generation of high quality of hepatocyte-like cells from induced pluripotent stem cells with Parp1 but lacking c-Myc. J Chin Med Assoc. 2018 Oct; 81(10):871-877.
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Homozygous KLF1 mutation c.901C>T (p.Arg301Cys) resulting in mild thalassemia intermedia in an Indian: A next-generation sequencing diagnosis. Blood Cells Mol Dis. 2018 09; 72:19-21.