Protein Interaction Domains and Motifs
"Protein Interaction Domains and Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein modules with conserved ligand-binding surfaces which mediate specific interaction functions in SIGNAL TRANSDUCTION PATHWAYS and the specific BINDING SITES of their cognate protein LIGANDS.
Descriptor ID |
D054730
|
MeSH Number(s) |
G02.111.570.820.709.275.750.500
|
Concept/Terms |
Protein Interaction Motifs- Protein Interaction Motifs
- Motif, Protein Interaction
- Motifs, Protein Interaction
- Protein Interaction Motif
- Binding Motifs, Protein Interaction
- Protein Interaction Binding Motifs
Protein Interaction Domains- Protein Interaction Domains
- Domain, Protein Interaction
- Domains, Protein Interaction
- Protein Interaction Domain
- Protein-Protein Interaction Domains
- Domain, Protein-Protein Interaction
- Domains, Protein-Protein Interaction
- Protein Protein Interaction Domains
- Protein-Protein Interaction Domain
|
Below are MeSH descriptors whose meaning is more general than "Protein Interaction Domains and Motifs".
Below are MeSH descriptors whose meaning is more specific than "Protein Interaction Domains and Motifs".
This graph shows the total number of publications written about "Protein Interaction Domains and Motifs" by people in this website by year, and whether "Protein Interaction Domains and Motifs" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2009 | 1 | 1 | 2 |
2010 | 1 | 0 | 1 |
2012 | 0 | 4 | 4 |
2013 | 0 | 5 | 5 |
2014 | 0 | 2 | 2 |
2016 | 1 | 5 | 6 |
2017 | 5 | 48 | 53 |
2018 | 4 | 27 | 31 |
2019 | 2 | 12 | 14 |
2020 | 1 | 39 | 40 |
2021 | 1 | 20 | 21 |
To return to the timeline, click here.
Below are the most recent publications written about "Protein Interaction Domains and Motifs" by people in Profiles.
-
In silico identification of novel SARS-COV-2 2'-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):727-736.
-
Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants. J Virol. 2021 09 09; 95(19):e0068521.
-
SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma. Proc Natl Acad Sci U S A. 2021 09 07; 118(36).
-
Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics. Elife. 2021 08 26; 10.
-
Comparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach. Biophys Chem. 2021 11; 278:106677.
-
A model for COVID-19-induced dysregulation of ACE2 shedding by ADAM17. Biochem Biophys Res Commun. 2021 10 08; 573:158-163.
-
Geraniin Inhibits the Entry of SARS-CoV-2 by Blocking the Interaction between Spike Protein RBD and Human ACE2 Receptor. Int J Mol Sci. 2021 Aug 10; 22(16).
-
Detection of Binding Sites on SARS-CoV-2 Spike Protein Receptor-Binding Domain by Molecular Dynamics Simulations in Mixed Solvents. IEEE/ACM Trans Comput Biol Bioinform. 2021 Jul-Aug; 18(4):1281-1289.
-
GB-2 blocking the interaction between ACE2 and wild type and mutation of spike protein of SARS-CoV-2. Biomed Pharmacother. 2021 Oct; 142:112011.
-
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro. Nat Commun. 2021 07 28; 12(1):4584.