STAT1 Transcription Factor
"STAT1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS.
| Descriptor ID |
D050794
|
| MeSH Number(s) |
D12.644.360.024.303.500.500 D12.644.360.024.342.100 D12.776.157.057.061.500.500 D12.776.157.057.186.100 D12.776.260.513.249.500 D12.776.476.024.386.500.500 D12.776.476.024.430.100 D12.776.930.354.249.500 D12.776.930.840.100
|
| Concept/Terms |
STAT1 Transcription Factor- STAT1 Transcription Factor
- Transcription Factor, STAT1
- Transcription Factor STAT91
- Gamma-Activated Factor, 91 kDa
- Gamma Activated Factor, 91 kDa
- STAT-91 Transcription Factor
- STAT 91 Transcription Factor
- Transcription Factor, STAT-91
- STAT-91 Protein
- STAT 91 Protein
- STAT91 Transcription Factor
- Transcription Factor, STAT91
- STAT1 Protein
- Signal Transducer and Activator of Transcription 1
|
Below are MeSH descriptors whose meaning is more general than "STAT1 Transcription Factor".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Adaptor Proteins, Signal Transducing [D12.644.360.024]
- Interferon-Stimulated Gene Factor 3 [D12.644.360.024.303]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.644.360.024.303.500]
- STAT1 Transcription Factor [D12.644.360.024.303.500.500]
- STAT Transcription Factors [D12.644.360.024.342]
- STAT1 Transcription Factor [D12.644.360.024.342.100]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Adaptor Proteins, Signal Transducing [D12.776.157.057]
- Interferon-Stimulated Gene Factor 3 [D12.776.157.057.061]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.157.057.061.500]
- STAT1 Transcription Factor [D12.776.157.057.061.500.500]
- STAT Transcription Factors [D12.776.157.057.186]
- STAT1 Transcription Factor [D12.776.157.057.186.100]
- DNA-Binding Proteins [D12.776.260]
- Interferon-Stimulated Gene Factor 3 [D12.776.260.513]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.260.513.249]
- STAT1 Transcription Factor [D12.776.260.513.249.500]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Adaptor Proteins, Signal Transducing [D12.776.476.024]
- Interferon-Stimulated Gene Factor 3 [D12.776.476.024.386]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.476.024.386.500]
- STAT1 Transcription Factor [D12.776.476.024.386.500.500]
- STAT Transcription Factors [D12.776.476.024.430]
- STAT1 Transcription Factor [D12.776.476.024.430.100]
- Transcription Factors [D12.776.930]
- Interferon-Stimulated Gene Factor 3 [D12.776.930.354]
- Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.930.354.249]
- STAT1 Transcription Factor [D12.776.930.354.249.500]
- STAT Transcription Factors [D12.776.930.840]
- STAT1 Transcription Factor [D12.776.930.840.100]
Below are MeSH descriptors whose meaning is more specific than "STAT1 Transcription Factor".
This graph shows the total number of publications written about "STAT1 Transcription Factor" by people in this website by year, and whether "STAT1 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 2 | 4 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 3 | 4 |
| 2017 | 16 | 7 | 23 |
| 2018 | 3 | 5 | 8 |
| 2019 | 3 | 2 | 5 |
| 2020 | 2 | 3 | 5 |
| 2021 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "STAT1 Transcription Factor" by people in Profiles.
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SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway. J Virol. 2021 09 09; 95(19):e0086221.
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SARS-CoV-2 suppresses IFNß production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon. PLoS Pathog. 2021 08; 17(8):e1009800.
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SARS-CoV-2 Spike protein enhances ACE2 expression via facilitating Interferon effects in bronchial epithelium. Immunol Lett. 2021 09; 237:33-41.
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Toward a Coronavirus Knowledge Graph. Genes (Basel). 2021 06 29; 12(7).
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Tofacitinib therapy intercepts macrophage metabolic reprogramming instigated by SARS-CoV-2 Spike protein. Eur J Immunol. 2021 09; 51(9):2330-2340.
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Fludarabine inhibits type I interferon-induced expression of the SARS-CoV-2 receptor angiotensin-converting enzyme 2. Cell Mol Immunol. 2021 07; 18(7):1829-1831.
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Control of Macrophage Inflammation by P2Y Purinergic Receptors. Cells. 2021 05 04; 10(5).
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Pharmacological mechanism of immunomodulatory agents for the treatment of severe cases of COVID-19 infection. Inflamm Res. 2021 Apr; 70(4):389-405.
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An integrative analysis identifying transcriptional features and key genes involved in COVID-19. Epigenomics. 2020 11; 12(22):1969-1981.
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Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoV. J Virol. 2020 11 09; 94(23).