Positive Regulatory Domain I-Binding Factor 1
"Positive Regulatory Domain I-Binding Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.
Descriptor ID |
D000074462
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MeSH Number(s) |
D08.811.913.555.500.800.700 D12.776.260.703.650 D12.776.930.780.904
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Concept/Terms |
Positive Regulatory Domain I-Binding Factor 1- Positive Regulatory Domain I-Binding Factor 1
- Positive Regulatory Domain I Binding Factor 1
- PRDI-BF1 Protein
- PRDI BF1 Protein
- B Lymphocyte-Induced Maturation Protein 1
- B Lymphocyte Induced Maturation Protein 1
- PRDM1 Protein
- BLIMP1 Protein
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Below are MeSH descriptors whose meaning is more general than "Positive Regulatory Domain I-Binding Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Positive Regulatory Domain I-Binding Factor 1".
This graph shows the total number of publications written about "Positive Regulatory Domain I-Binding Factor 1" by people in this website by year, and whether "Positive Regulatory Domain I-Binding Factor 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 0 | 4 | 4 |
2018 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Positive Regulatory Domain I-Binding Factor 1" by people in Profiles.
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Hallmarks of the aging T-cell system. FEBS J. 2021 12; 288(24):7123-7142.
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Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation. Nat Immunol. 2019 03; 20(3):288-300.
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The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation. Immunity. 2018 04 17; 48(4):659-674.e6.
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New Insights into the Genetic Basis of Monge's Disease and Adaptation to High-Altitude. Mol Biol Evol. 2017 Dec 01; 34(12):3154-3168.
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Virus-Like Vesicles of Kaposi's Sarcoma-Associated Herpesvirus Activate Lytic Replication by Triggering Differentiation Signaling. J Virol. 2017 08 01; 91(15).
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A distinct subpopulation of CD25- T-follicular regulatory cells localizes in the germinal centers. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):E6400-E6409.
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Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis. Ann Rheum Dis. 2017 Jun; 76(6):1150-1158.
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The aryl hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med. 2017 01; 214(1):197-208.
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Retinoic acid improves defective TLR9/RP105-induced immune responses in common variable immunodeficiency-derived B cells. J Immunol. 2013 Oct 01; 191(7):3624-33.