Zinc Finger E-box-Binding Homeobox 1
"Zinc Finger E-box-Binding Homeobox 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor characterized by N-terminal and C-terminal CYS2-HIS2 ZINC FINGERS separated by a homeobox. It represses the expression of E-CADHERIN to induce the EPITHELIAL-MESENCHYMAL TRANSITION. It also represses PROTO-ONCOGENE PROTEINS C-BCL-6; regulates the cell type-specific expression of SODIUM-POTASSIUM-EXCHANGING ATPASE; and promotes neuronal differentiation.
| Descriptor ID |
D000071799
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| MeSH Number(s) |
D12.776.260.400.906 D12.776.260.703.800 D12.776.930.780.945
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| Concept/Terms |
Zinc Finger E-box-Binding Homeobox 1- Zinc Finger E-box-Binding Homeobox 1
- Zinc Finger E box Binding Homeobox 1
- NIL-2-A Zinc Finger Protein
- NIL 2 A Zinc Finger Protein
- TCF8 Protein
- Zeb1 Transcription Factor
- Transcription Factor, Zeb1
- Transcription Factor 8
|
Below are MeSH descriptors whose meaning is more general than "Zinc Finger E-box-Binding Homeobox 1".
Below are MeSH descriptors whose meaning is more specific than "Zinc Finger E-box-Binding Homeobox 1".
This graph shows the total number of publications written about "Zinc Finger E-box-Binding Homeobox 1" by people in this website by year, and whether "Zinc Finger E-box-Binding Homeobox 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 3 | 1 | 4 |
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Below are the most recent publications written about "Zinc Finger E-box-Binding Homeobox 1" by people in Profiles.
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CircLRP6 Regulation of ZEB1 via miR-455 Is Involved in the Epithelial-Mesenchymal Transition During Arsenite-Induced Malignant Transformation of Human Keratinocytes. Toxicol Sci. 2018 04 01; 162(2):450-461.
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Tumor suppressor miR-128-3p inhibits metastasis and epithelial-mesenchymal transition by targeting ZEB1 in esophageal squamous-cell cancer. Acta Biochim Biophys Sin (Shanghai). 2018 Feb 01; 50(2):171-180.
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The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression. Cell Death Dis. 2018 01 19; 9(2):66.
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miR-200c inhibits TGF-ß-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer. Cancer Gene Ther. 2018 05; 25(3-4):68-76.
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Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma. Oncol Rep. 2018 Jan; 39(1):91-100.
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N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration. Genome Biol. 2017 05 24; 18(1):98.
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ZEB1 expression in Chinese lower-grade gliomas. J Neurooncol. 2017 05; 133(1):213-215.
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Changes in microRNA expression during disease progression in patients with chronic viral hepatitis. Liver Int. 2015 Apr; 35(4):1324-33.