Glycogen Synthase Kinase 3 beta
"Glycogen Synthase Kinase 3 beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.
Descriptor ID |
D000071679
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MeSH Number(s) |
D05.500.117.875.500 D08.811.913.696.620.682.700.429.500.500 D08.811.913.696.620.682.700.646.625.500 D12.644.360.300.500.500 D12.776.476.081.875.500 D12.776.476.300.500.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3 beta".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3 beta".
This graph shows the total number of publications written about "Glycogen Synthase Kinase 3 beta" by people in this website by year, and whether "Glycogen Synthase Kinase 3 beta" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 2 | 2 |
2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2017 | 7 | 7 | 14 |
2018 | 2 | 7 | 9 |
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Below are the most recent publications written about "Glycogen Synthase Kinase 3 beta" by people in Profiles.
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Multifunctional inhibitors of SARS-CoV-2 by MM/PBSA, essential dynamics, and molecular dynamic investigations. J Mol Graph Model. 2021 09; 107:107969.
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Lithium chloride combination with rapamycin for the treatment of COVID-19 pneumonia. Med Hypotheses. 2020 09; 142:109798.
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Is GSK3ß a molecular target of chloroquine treatment against COVID-19? Drug Discov Ther. 2020 May 06; 14(2):107-108.
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Polymorphisms associated with oral clefts as potential susceptibility markers for oral and breast cancer. Arch Oral Biol. 2019 Mar; 99:9-14.
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Polydatin Prevents Lipopolysaccharide (LPS)-Induced Parkinson's Disease via Regulation of the AKT/GSK3ß-Nrf2/NF-?B Signaling Axis. Front Immunol. 2018; 9:2527.
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GSK3ß inhibition attenuates LPS-induced IL-6 expression in porcine adipocytes. Sci Rep. 2018 10 29; 8(1):15967.
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PI3K/AKT/GSK3ß/CRMP-2-mediated neuroplasticity in depression induced by stress. Neuroreport. 2018 10 17; 29(15):1256-1263.
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Characterisation of mesenchymal colon tumour-derived cells in tumourspheres as a model for colorectal cancer progression. Int J Oncol. 2018 Dec; 53(6):2379-2396.
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Cracking novel shared targets between epilepsy and Alzheimer's disease: need of the hour. Rev Neurosci. 2018 Jun 27; 29(4):425-442.
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Tiotropium inhibits methacholine-induced extracellular matrix production via ß-catenin signaling in human airway smooth muscle cells. Int J Chron Obstruct Pulmon Dis. 2018; 13:1469-1481.