Leukocyte Immunoglobulin-like Receptor B1
"Leukocyte Immunoglobulin-like Receptor B1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor for HISTOCOMPATIBILITY ANTIGENS CLASS I that also functions as a receptor for the UL18 protein, an MHC class I homolog expressed by human CYTOMEGALOVIRUS. It consists of four Ig-like C2 domains and is expressed primarily by B-cells and MONOCYTES, as well as DENDRITIC CELLS; its interaction with MHC1 functions to down-regulate the immune response.
Descriptor ID |
D000075362
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MeSH Number(s) |
D12.776.543.750.705.023
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Concept/Terms |
Leukocyte Immunoglobulin-like Receptor B1- Leukocyte Immunoglobulin-like Receptor B1
- Leukocyte Immunoglobulin like Receptor B1
- CD85J Antigen
- Antigen, CD85J
- Immunoglobulin-like Transcript 2 Protein
- Immunoglobulin like Transcript 2 Protein
- Leukocyte Ig-like Receptor B1
- Leukocyte Ig like Receptor B1
- LIR-1 Protein
- LIR 1 Protein
- ILT2 Protein
- LILRB1
- CD85 Antigen
- Antigen, CD85
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Below are MeSH descriptors whose meaning is more general than "Leukocyte Immunoglobulin-like Receptor B1".
Below are MeSH descriptors whose meaning is more specific than "Leukocyte Immunoglobulin-like Receptor B1".
This graph shows the total number of publications written about "Leukocyte Immunoglobulin-like Receptor B1" by people in this website by year, and whether "Leukocyte Immunoglobulin-like Receptor B1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 2 | 3 |
2018 | 1 | 1 | 2 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukocyte Immunoglobulin-like Receptor B1" by people in Profiles.
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Structures of the fourĀ Ig-like domain LILRB2 and the four-domain LILRB1 and HLA-G1 complex. Cell Mol Immunol. 2020 09; 17(9):966-975.
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LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions. J Clin Invest. 2018 04 02; 128(4):1523-1537.
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Inhibiting HLA-G restores IFN-? and TNF-a producing T cell in pleural Tuberculosis. Tuberculosis (Edinb). 2018 03; 109:69-79.
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Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors. Immunity. 2017 12 19; 47(6):1100-1113.e6.
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Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy. Nat Immunol. 2018 Jan; 19(1):76-84.
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Dengue virus compartmentalization during antibody-enhanced infection. Sci Rep. 2017 01 13; 7:40923.