Costimulatory and Inhibitory T-Cell Receptors
"Costimulatory and Inhibitory T-Cell Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE.
Descriptor ID |
D061025
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MeSH Number(s) |
D12.776.543.750.705.222
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Concept/Terms |
Costimulatory and Inhibitory T-Cell Receptors- Costimulatory and Inhibitory T-Cell Receptors
- Costimulatory and Inhibitory T Cell Receptors
- Costimulatory and Inhibitory T-Lymphocyte Receptors
- Costimulatory and Inhibitory T Lymphocyte Receptors
- Receptors, Costimulatory and Inhibitory, T-Lymphocyte
Costimulatory T-Cell Receptors- Costimulatory T-Cell Receptors
- Costimulatory T Cell Receptors
- Receptors, Costimulatory T-Cell
- T-Cell Receptors, Costimulatory
- Receptors, Costimulatory, T-Lymphocyte
- Costimulatory T-Lymphocyte Receptors
- Costimulatory T Lymphocyte Receptors
- Receptors, Costimulatory T-Lymphocyte
- T-Lymphocyte Receptors, Costimulatory
Inhibitory T-Cell Receptors- Inhibitory T-Cell Receptors
- Inhibitory T Cell Receptors
- Receptors, Inhibitory T-Cell
- T-Cell Receptors, Inhibitory
- Receptors, Inhibitory, T-Cell
- Inhibitory T-Lymphocyte Receptors
- Inhibitory T Lymphocyte Receptors
- Receptors, Inhibitory T-Lymphocyte
- T-Lymphocyte Receptors, Inhibitory
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Below are MeSH descriptors whose meaning is more general than "Costimulatory and Inhibitory T-Cell Receptors".
Below are MeSH descriptors whose meaning is more specific than "Costimulatory and Inhibitory T-Cell Receptors".
This graph shows the total number of publications written about "Costimulatory and Inhibitory T-Cell Receptors" by people in this website by year, and whether "Costimulatory and Inhibitory T-Cell Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
2017 | 3 | 3 | 6 |
2018 | 1 | 3 | 4 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Costimulatory and Inhibitory T-Cell Receptors" by people in Profiles.
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Systems-Level Immune Monitoring by Mass Cytometry. Methods Mol Biol. 2019; 1913:33-48.
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Association Between Immune-related Adverse Events and Efficacy of Immune Checkpoint Inhibitors in Non-small-cell Lung Cancer. Clin Lung Cancer. 2019 05; 20(3):201-207.
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INfluenza Vaccine Indication During therapy with Immune checkpoint inhibitors: a transversal challenge. The INVIDIa study. Immunotherapy. 2018 10; 10(14):1229-1239.
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The current state of immune checkpoint inhibitors in the first-line treatment of renal cancer. Immunotherapy. 2018 09; 10(12):1047-1052.
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First person: Antoni Ribas, MD, PhD: The physician-scientist from the University of California at Los Angeles researches how new therapies for patients with advanced malignant melanoma can help to overcome resistance to treatment. Cancer. 2018 03 15; 124(6):1097-1098.
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Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection. J Virol. 2017 12 01; 91(23).
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Immunotherapy of cancers comes of age. Expert Rev Clin Immunol. 2017 10; 13(10):1001-1015.
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T-cell-associated immunotherapy: a promising strategy for the treatment of hepatocellular carcinoma. Immunotherapy. 2017 06; 9(7):523-525.
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Checkpoint inhibitors in gastrointestinal cancers: Expectations and reality. World J Gastroenterol. 2017 May 07; 23(17):3017-3021.
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The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression. Nat Commun. 2017 03 09; 8:14638.