"Complement Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequential activation of serum COMPLEMENT PROTEINS to create the COMPLEMENT MEMBRANE ATTACK COMPLEX. Factors initiating complement activation include ANTIGEN-ANTIBODY COMPLEXES, microbial ANTIGENS, or cell surface POLYSACCHARIDES.
| Descriptor ID |
D003167
|
| MeSH Number(s) |
G12.274
|
| Concept/Terms |
Complement Activation- Complement Activation
- Activation, Complement
- Activations, Complement
- Complement Activations
|
Below are MeSH descriptors whose meaning is more general than "Complement Activation".
Below are MeSH descriptors whose meaning is more specific than "Complement Activation".
This graph shows the total number of publications written about "Complement Activation" by people in this website by year, and whether "Complement Activation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 7 | 9 | 16 |
| 2018 | 6 | 7 | 13 |
| 2019 | 3 | 5 | 8 |
| 2020 | 13 | 12 | 25 |
| 2021 | 8 | 8 | 16 |
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Below are the most recent publications written about "Complement Activation" by people in Profiles.
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The case of complement inhibitors. Adv Biol Regul. 2021 08; 81:100822.
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Transcriptome Analysis of Peripheral Blood Mononuclear Cells Reveals Distinct Immune Response in Asymptomatic and Re-Detectable Positive COVID-19 Patients. Front Immunol. 2021; 12:716075.
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Erythrocytes identify complement activation in patients with COVID-19. Am J Physiol Lung Cell Mol Physiol. 2021 08 01; 321(2):L485-L489.
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Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins. Front Immunol. 2021; 12:714511.
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Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology. PLoS Pathog. 2021 07; 17(7):e1009381.
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Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19. Adv Drug Deliv Rev. 2021 11; 178:113848.
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Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity. Front Endocrinol (Lausanne). 2021; 12:658304.
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Allergenic components of the mRNA-1273 vaccine for COVID-19: Possible involvement of polyethylene glycol and IgG-mediated complement activation. Allergy. 2021 11; 76(11):3307-3313.
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Complement-Induced Endotheliopathy-Associated Vascular Microthrombosis in Coronavirus Disease 2019. J Infect Dis. 2021 06 15; 223(12):2198-2199.
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Immunothrombotic dysregulation in chagas disease and COVID-19: a comparative study of anticoagulation. Mol Cell Biochem. 2021 Oct; 476(10):3815-3825.