"Antigen Presentation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which antigen is presented to lymphocytes in a form they can recognize. This is performed by antigen presenting cells (APCs). Some antigens require processing before they can be recognized. Antigen processing consists of ingestion and partial digestion of the antigen by the APC, followed by presentation of fragments on the cell surface. (From Rosen et al., Dictionary of Immunology, 1989)
| Descriptor ID |
D017951
|
| MeSH Number(s) |
G12.119 G12.450.050.400.070
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Antigen Presentation".
Below are MeSH descriptors whose meaning is more specific than "Antigen Presentation".
This graph shows the total number of publications written about "Antigen Presentation" by people in this website by year, and whether "Antigen Presentation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 4 | 4 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2016 | 1 | 2 | 3 |
| 2017 | 3 | 17 | 20 |
| 2018 | 6 | 16 | 22 |
| 2019 | 3 | 8 | 11 |
| 2020 | 1 | 2 | 3 |
| 2021 | 2 | 6 | 8 |
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Below are the most recent publications written about "Antigen Presentation" by people in Profiles.
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Self-assembling synthetic nanoadjuvant scaffolds cross-link B cell receptors and represent new platform technology for therapeutic antibody production. Sci Adv. 2021 08; 7(32).
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CD169 Defines Activated CD14+ Monocytes With Enhanced CD8+ T Cell Activation Capacity. Front Immunol. 2021; 12:697840.
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Influence of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Population and Individual Level. Front Immunol. 2021; 12:669357.
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Single-cell RNA sequencing identify SDCBP in ACE2-positive bronchial epithelial cells negatively correlates with COVID-19 severity. J Cell Mol Med. 2021 07; 25(14):7001-7012.
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The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-?. Proc Natl Acad Sci U S A. 2021 06 08; 118(23).
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Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics. Cell Rep. 2021 06 29; 35(13):109305.
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Profiling SARS-CoV-2 HLA-I peptidome reveals TÂ cell epitopes from out-of-frame ORFs. Cell. 2021 07 22; 184(15):3962-3980.e17.
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Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells. Cell Rep. 2021 05 25; 35(8):109179.
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Single-cell RNA sequencing of blood antigen-presenting cells in severe COVID-19 reveals multi-process defects in antiviral immunity. Nat Cell Biol. 2021 05; 23(5):538-551.
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Antigen presentation in SARS-CoV-2 infection: the role of class I HLA and ERAP polymorphisms. Hum Immunol. 2021 Aug; 82(8):551-560.