"Exoribonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the exonucleolytic cleavage of RNA. It includes EC 3.1.13.-, EC 3.1.14.-, EC 3.1.15.-, and EC 3.1.16.-. EC 3.1.-
| Descriptor ID |
D005095
|
| MeSH Number(s) |
D08.811.277.352.365.300 D08.811.277.352.700.375
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Exoribonucleases".
Below are MeSH descriptors whose meaning is more specific than "Exoribonucleases".
This graph shows the total number of publications written about "Exoribonucleases" by people in this website by year, and whether "Exoribonucleases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 3 | 0 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 3 | 1 | 4 |
| 2019 | 0 | 3 | 3 |
| 2020 | 5 | 2 | 7 |
| 2021 | 5 | 3 | 8 |
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Below are the most recent publications written about "Exoribonucleases" by people in Profiles.
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Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme. Science. 2021 Sep 03; 373(6559):1142-1146.
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Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase. Antiviral Res. 2021 09; 193:105142.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease. Biochem J. 2021 07 16; 478(13):2445-2464.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase. Biochem J. 2021 07 16; 478(13):2481-2497.
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Immunity and Viral Infections: Modulating Antiviral Response via CRISPR-Cas Systems. Viruses. 2021 07 15; 13(7).
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Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors. SLAS Discov. 2021 10; 26(9):1200-1211.
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The Antiviral Effect of the Chemical Compounds Targeting DED/EDh Motifs of the Viral Proteins on Lymphocytic Choriomeningitis Virus and SARS-CoV-2. Viruses. 2021 06 24; 13(7).
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The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors. ACS Infect Dis. 2021 08 13; 7(8):2214-2220.
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Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein. Proc Natl Acad Sci U S A. 2021 06 15; 118(24).
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Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading. Cell. 2021 06 24; 184(13):3474-3485.e11.