"Osteopontin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabolism and a variety of other biological functions. Cell signaling by osteopontin may occur through a cell adhesion sequence that recognizes INTEGRIN ALPHA-V BETA-3.
Descriptor ID |
D053495
|
MeSH Number(s) |
D12.644.276.374.625 D12.776.395.700.837 D12.776.467.374.625 D12.776.860.300.762 D23.529.374.625
|
Concept/Terms |
Osteopontin- Osteopontin
- Sialoprotein 1
- Secreted Phosphoprotein 1
- Bone Sialoprotein 1
- Sialoprotein 1, Bone
- Bone Sialoprotein I
- Sialoprotein I, Bone
|
Below are MeSH descriptors whose meaning is more general than "Osteopontin".
Below are MeSH descriptors whose meaning is more specific than "Osteopontin".
This graph shows the total number of publications written about "Osteopontin" by people in this website by year, and whether "Osteopontin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2010 | 2 | 0 | 2 |
2015 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2017 | 8 | 6 | 14 |
2018 | 7 | 2 | 9 |
2019 | 4 | 2 | 6 |
2020 | 2 | 0 | 2 |
2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Osteopontin" by people in Profiles.
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COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes. JCI Insight. 2021 06 18; 6(13).
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High Levels of the Cleaved Form of Galectin-9 and Osteopontin in the Plasma Are Associated with Inflammatory Markers That Reflect the Severity of COVID-19 Pneumonia. Int J Mol Sci. 2021 May 07; 22(9).
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High levels of circulating osteopontin in inflammatory lung disease regardless of Sars-CoV-2 infection. EMBO Mol Med. 2021 05 07; 13(5):e14124.
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Relationship between serum osteopontin levels and the severity of COVID-19 infection. Wien Klin Wochenschr. 2021 Apr; 133(7-8):298-302.
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The Potential Role of Osteopontin and Furin in Worsening Disease Outcomes in COVID-19 Patients with Pre-Existing Diabetes. Cells. 2020 11 23; 9(11).
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Osteoprotegerin and Osteopontin Serum Levels are Associated with Vascular Function and Inflammation in Coronary Artery Disease Patients. Curr Vasc Pharmacol. 2020; 18(5):523-530.
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Biomarkers for malignant pleural mesothelioma: a meta-analysis. Carcinogenesis. 2019 Nov 25; 40(11):1320-1331.
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Exercise Mitigates Bone Loss in Women With Severe Obesity After Roux-en-Y Gastric Bypass: A Randomized Controlled Trial. J Clin Endocrinol Metab. 2019 10 01; 104(10):4639-4650.
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Baseline serum levels of osteopontin predict clinical response to treatment with nivolumab in patients with non-small cell lung cancer. Clin Exp Metastasis. 2019 10; 36(5):449-456.
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Vitamin D: A cardiovascular risk biomarker or a treatment target? Hellenic J Cardiol. 2019 Mar - Apr; 60(2):114-116.