"Pyrrolidines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds also known as tetrahydropyridines with general molecular formula (CH2)4NH.
Descriptor ID |
D011759
|
MeSH Number(s) |
D03.383.773
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrrolidines".
Below are MeSH descriptors whose meaning is more specific than "Pyrrolidines".
This graph shows the total number of publications written about "Pyrrolidines" by people in this website by year, and whether "Pyrrolidines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 2 | 0 | 2 |
2006 | 0 | 3 | 3 |
2011 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2014 | 0 | 2 | 2 |
2017 | 7 | 32 | 39 |
2018 | 8 | 19 | 27 |
2019 | 1 | 4 | 5 |
2020 | 3 | 3 | 6 |
2021 | 7 | 5 | 12 |
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Below are the most recent publications written about "Pyrrolidines" by people in Profiles.
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Qing-Fei-Pai-Du decoction and wogonoside exert anti-inflammatory action through down-regulating USP14 to promote the degradation of activating transcription factor 2. FASEB J. 2021 09; 35(9):e21870.
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Efficacy and safety of sofosbuvir plus daclatasvir or ravidasvir in patients with COVID-19: A randomized controlled trial. J Med Virol. 2021 12; 93(12):6750-6759.
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Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2021 07 20; 118(29).
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Redox-Mediated Artificial Non-Enzymatic Antioxidant MXene Nanoplatforms for Acute Kidney Injury Alleviation. Adv Sci (Weinh). 2021 09; 8(18):e2101498.
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Efficacy of combined Sofosbuvir and Daclatasvir in the treatment of COVID-19 patients with pneumonia: a multicenter Egyptian study. Expert Rev Anti Infect Ther. 2022 02; 20(2):291-295.
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Clinical efficacy of antiviral agents against coronavirus disease 2019: A systematic review of randomized controlled trials. J Microbiol Immunol Infect. 2021 Oct; 54(5):767-775.
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Zinc supplementation augments the suppressive effects of repurposed NF-?B inhibitors on ACE2 expression in human lung cell lines. Life Sci. 2021 Sep 01; 280:119752.
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In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19. J Antimicrob Chemother. 2021 06 18; 76(7):1874-1885.
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Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies. Eur J Med Chem. 2021 Oct 15; 222:113584.
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Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors. J Med Chem. 2022 02 24; 65(4):2848-2865.