"Furans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds with a 5-membered ring of four carbons and an oxygen. They are aromatic heterocycles. The reduced form is tetrahydrofuran.
| Descriptor ID |
D005663
|
| MeSH Number(s) |
D03.383.312
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Furans".
Below are MeSH descriptors whose meaning is more specific than "Furans".
This graph shows the total number of publications written about "Furans" by people in this website by year, and whether "Furans" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 4 | 3 | 7 |
| 2018 | 5 | 3 | 8 |
| 2019 | 3 | 5 | 8 |
| 2020 | 2 | 1 | 3 |
| 2021 | 1 | 4 | 5 |
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Below are the most recent publications written about "Furans" by people in Profiles.
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease. Biochem J. 2021 07 16; 478(13):2517-2531.
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In vitro activity of itraconazole against SARS-CoV-2. J Med Virol. 2021 Jul; 93(7):4454-4460.
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A combined assay for quantifying remdesivir and its metabolite, along with dexamethasone, in serum. J Antimicrob Chemother. 2021 06 18; 76(7):1865-1873.
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Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID-19. Pharmacol Res Perspect. 2021 04; 9(2):e00743.
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Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor. Clin Pharmacokinet. 2021 05; 60(5):569-583.
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Field-Template, QSAR, Ensemble Molecular Docking, and 3D-RISM Solvation Studies Expose Potential of FDA-Approved Marine Drugs as SARS-CoVID-2 Main Protease Inhibitors. Molecules. 2021 Feb 10; 26(4).
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Simultaneous quantification of seven repurposed COVID-19 drugs remdesivir (plus metabolite GS-441524), chloroquine, hydroxychloroquine, lopinavir, ritonavir, favipiravir and azithromycin by a two-dimensional isotope dilution LC-MS/MS method in human serum. J Pharm Biomed Anal. 2021 Mar 20; 196:113935.
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Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies. Anal Biochem. 2021 03 15; 617:114118.
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Role of OATP4C1 in Renal Handling of Remdesivir and its Nucleoside Analog GS-441524: The First Approved Drug for Patients with COVID-19. J Pharm Pharm Sci. 2021; 24:227-236.
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Simulation of Remdesivir Pharmacokinetics and Its Drug Interactions. J Pharm Pharm Sci. 2021; 24:277-291.