"Receptors, Glucagon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors that bind glucagon with high affinity and trigger intracellular changes which influence the behavior of cells. Activation of glucagon receptors causes a variety of effects; the best understood is the initiation of a complex enzymatic cascade in the liver which ultimately increases the availability of glucose to body organs.
Descriptor ID |
D018027
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MeSH Number(s) |
D12.776.543.750.695.330 D12.776.543.750.750.580.350
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptors, Glucagon".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Glucagon".
This graph shows the total number of publications written about "Receptors, Glucagon" by people in this website by year, and whether "Receptors, Glucagon" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2017 | 2 | 0 | 2 |
2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "Receptors, Glucagon" by people in Profiles.
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Sterically Shielded, Stabilized Nitrile Imine for Rapid Bioorthogonal Protein Labeling in Live Cells. J Am Chem Soc. 2018 04 11; 140(14):4860-4868.
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Hepatic Gi signaling regulates whole-body glucose homeostasis. J Clin Invest. 2018 02 01; 128(2):746-759.
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Structure of the glucagon receptor in complex with a glucagon analogue. Nature. 2018 01 03; 553(7686):106-110.
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Investigational glucagon receptor antagonists in Phase I and II clinical trials for diabetes. Expert Opin Investig Drugs. 2017 Dec; 26(12):1373-1389.
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Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 2017 06 08; 546(7657):259-264.
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Central Nervous System Regulation of Intestinal Lipoprotein Metabolism by Glucagon-Like Peptide-1 via a Brain-Gut Axis. Arterioscler Thromb Vasc Biol. 2015 May; 35(5):1092-100.
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A randomized controlled trial comparing the GLP-1 receptor agonist liraglutide to a sulphonylurea as add on to metformin in patients with established type 2 diabetes during Ramadan: the Treat 4 Ramadan Trial. Diabetes Obes Metab. 2014 Jun; 16(6):527-36.