In Situ Nick-End Labeling
"In Situ Nick-End Labeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
| Descriptor ID |
D020287
|
| MeSH Number(s) |
E05.393.475
|
| Concept/Terms |
In Situ Nick-End Labeling- In Situ Nick-End Labeling
- TUNEL
- Nick-End Labeling, In Situ
- In Situ Nick End Labelling
- In Situ Nick End Labeling
- In Situ Nick End-Labelling
- In Situ Nick-End Labelling
- Nick End-Labeling, In Situ
- Nick End Labeling, In Situ
- Nick End-Labelling, In Situ
- Nick End Labelling, In Situ
- Nick-End Labelling, In Situ
- In Situ Nick End-Labeling
|
Below are MeSH descriptors whose meaning is more general than "In Situ Nick-End Labeling".
Below are MeSH descriptors whose meaning is more specific than "In Situ Nick-End Labeling".
This graph shows the total number of publications written about "In Situ Nick-End Labeling" by people in this website by year, and whether "In Situ Nick-End Labeling" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 8 | 8 |
| 2018 | 0 | 5 | 5 |
| 2019 | 0 | 3 | 3 |
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Below are the most recent publications written about "In Situ Nick-End Labeling" by people in Profiles.
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a-Hederin Induces Apoptosis of Esophageal Squamous Cell Carcinoma via an Oxidative and Mitochondrial-Dependent Pathway. Dig Dis Sci. 2019 12; 64(12):3528-3538.
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Dual Delivery of HNF4a and Cisplatin by Mesoporous Silica Nanoparticles Inhibits Cancer Pluripotency and Tumorigenicity in Hepatoma-Derived CD133-Expressing Stem Cells. ACS Appl Mater Interfaces. 2019 Jun 05; 11(22):19808-19818.
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miRNA-200b improves hepatic fibrosis induced by CCL4 by regulating toll-like receptor 4 in mice. J Cell Biochem. 2019 08; 120(8):13254-13261.
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Role of Sirolimus in renal tubular apoptosis in response to unilateral ureteral obstruction. Int J Med Sci. 2018; 15(13):1433-1442.
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Mulberrin (Mul) reduces spinal cord injury (SCI)-induced apoptosis, inflammation and oxidative stress in rats via miroRNA-337 by targeting Nrf-2. Biomed Pharmacother. 2018 Nov; 107:1480-1487.
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Antiarrhythmic effect linked to melatonin cardiorenal protection involves AT1 reduction and Hsp70-VDR increase. J Pineal Res. 2018 Nov; 65(4):e12513.
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Pretreatment With Argon Protects Human Cardiac Myocyte-Like Progenitor Cells from Oxygen Glucose Deprivation-Induced Cell Death by Activation of AKT and Differential Regulation of Mapkinases. Shock. 2018 05; 49(5):556-563.
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Nicorandil reduces burn wound progression by enhancing skin blood flow. J Plast Reconstr Aesthet Surg. 2018 08; 71(8):1196-1206.
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[Transhepatic arterial embolization with superparamagnetic iron oxide and lipiodol for the treatment of VX2 tumor in rabbits]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2017 Nov 28; 42(11):1248-1256.
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Dengue fatal cases present virus-specific HMGB1 response in peripheral organs. Sci Rep. 2017 11 22; 7(1):16011.