"Gene Targeting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.
| Descriptor ID |
D018390
|
| MeSH Number(s) |
E05.393.335
|
| Concept/Terms |
Gene Targeting- Gene Targeting
- Gene Targetings
- Targeting, Gene
- Targetings, Gene
|
Below are MeSH descriptors whose meaning is more general than "Gene Targeting".
Below are MeSH descriptors whose meaning is more specific than "Gene Targeting".
This graph shows the total number of publications written about "Gene Targeting" by people in this website by year, and whether "Gene Targeting" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 3 | 3 | 6 |
| 2019 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Gene Targeting" by people in Profiles.
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Exploring the Potential Mechanism of Shufeng Jiedu Capsule for Treating COVID-19 by Comprehensive Network Pharmacological Approaches and Molecular Docking Validation. Comb Chem High Throughput Screen. 2021; 24(9):1377-1394.
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CRISPR vs COVID-19: how can gene editing help beat a virus? Biotechniques. 2020 11; 69(5):327-329.
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Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Huashi Baidu formula in the treatment of COVID-19. Drug Dev Ind Pharm. 2020 Aug; 46(8):1345-1353.
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Moral reasons to edit the human genome: picking up from the Nuffield report. J Med Ethics. 2019 08; 45(8):514-523.
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A CRISPR-Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes. Nat Biotechnol. 2018 12; 36(11):1062-1066.
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MiR-129 regulates growth and invasion by targeting MAL2 in papillary thyroid carcinoma. Biomed Pharmacother. 2018 Sep; 105:1072-1078.
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Designer nuclease-mediated gene correction via homology-directed repair in an in vitro model of canine hemophilia B. J Gene Med. 2018 05; 20(5):e3020.
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The tumor suppressive TGF-ß/SMAD1/S1PR2 signaling axis is recurrently inactivated in diffuse large B-cell lymphoma. Blood. 2018 05 17; 131(20):2235-2246.
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Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery. Hum Mol Genet. 2018 03 01; 27(5):761-779.
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Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers. Cell Death Dis. 2018 01 17; 9(2):21.