Nucleic Acid Hybridization
"Nucleic Acid Hybridization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Descriptor ID |
D009693
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MeSH Number(s) |
E05.393.661 G02.111.611
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Concept/Terms |
Nucleic Acid Hybridization- Nucleic Acid Hybridization
- Acid Hybridization, Nucleic
- Acid Hybridizations, Nucleic
- Hybridization, Nucleic Acid
- Hybridizations, Nucleic Acid
- Nucleic Acid Hybridizations
Genomic Hybridization- Genomic Hybridization
- Genomic Hybridizations
- Hybridization, Genomic
- Hybridizations, Genomic
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Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Hybridization".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Hybridization".
This graph shows the total number of publications written about "Nucleic Acid Hybridization" by people in this website by year, and whether "Nucleic Acid Hybridization" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2005 | 1 | 1 | 2 |
2008 | 1 | 0 | 1 |
2009 | 0 | 2 | 2 |
2011 | 0 | 1 | 1 |
2017 | 1 | 13 | 14 |
2018 | 2 | 3 | 5 |
2019 | 0 | 5 | 5 |
2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Nucleic Acid Hybridization" by people in Profiles.
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Rapid and Sensitive Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in Label-Free Manner Using Micromechanical Sensors. Sensors (Basel). 2021 Jun 29; 21(13).
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Padlock probe-based rolling circle amplification lateral flow assay for point-of-need nucleic acid detection. Analyst. 2021 Jun 28; 146(13):4340-4347.
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Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9. Science. 2021 05 28; 372(6545):941-948.
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Point-of-care bulk testing for SARS-CoV-2 by combining hybridization capture with improved colorimetric LAMP. Nat Commun. 2021 03 05; 12(1):1467.
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Thermodynamic evaluation of the impact of DNA mismatches in PCR-type SARS-CoV-2 primers and probes. Mol Cell Probes. 2021 04; 56:101707.
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CRISPR-Assisted DNA Detection: A Novel dCas9-Based DNA Detection Technique. CRISPR J. 2020 12; 3(6):487-502.
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Human virus detection with graphene-based materials. Biosens Bioelectron. 2020 Oct 15; 166:112436.
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Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection. ACS Nano. 2020 May 26; 14(5):5268-5277.
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Leptospira yasudae sp. nov. and Leptospira stimsonii sp. nov., two new species of the pathogenic group isolated from environmental sources. Int J Syst Evol Microbiol. 2020 Mar; 70(3):1450-1456.
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Draft genome and description of Chryseobacterium phocaeense sp. nov.: a new bacterial species isolated from the sputum of a cystic fibrosis patient. Arch Microbiol. 2019 Dec; 201(10):1361-1368.