"Hedgehog Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of intercellular signaling proteins that play an important role in regulating the development of many TISSUES and organs. Their name derives from the observation of a hedgehog-like appearance in DROSOPHILA embryos with genetic mutations that block their action.
Descriptor ID |
D053823
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MeSH Number(s) |
D12.644.276.671 D12.776.467.671 D23.529.671
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hedgehog Proteins".
Below are MeSH descriptors whose meaning is more specific than "Hedgehog Proteins".
This graph shows the total number of publications written about "Hedgehog Proteins" by people in this website by year, and whether "Hedgehog Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2016 | 1 | 1 | 2 |
2017 | 7 | 6 | 13 |
2018 | 7 | 5 | 12 |
2019 | 3 | 0 | 3 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hedgehog Proteins" by people in Profiles.
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How does Covid-19 infection affect smell? Am J Otolaryngol. 2021 May-Jun; 42(3):102912.
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Patients with advanced basal cell carcinomas in treatment with sonic hedgehog inhibitors during the coronavirus disease 2019 (COVID-19) period: Management and adherence to treatment. J Am Acad Dermatol. 2020 06; 82(6):e205.
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A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling. Cell Chem Biol. 2019 08 15; 26(8):1143-1158.e6.
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Hedgehog Signaling Regulates Taste Organs and Oral Sensation: Distinctive Roles in the Epithelium, Stroma, and Innervation. Int J Mol Sci. 2019 Mar 16; 20(6).
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Targeting Hedgehog signaling pathway: Paving the road for cancer therapy. Pharmacol Res. 2019 03; 141:466-480.
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Managing adverse effects by dose reduction during routine treatment of locally advanced basal cell carcinoma with the hedgehog inhibitor vismodegib: a single centre experience. J Eur Acad Dermatol Venereol. 2019 Apr; 33(4):e144-e145.
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Microparticles Carrying Sonic Hedgehog Are Increased in Humans with Peripheral Artery Disease. Int J Mol Sci. 2018 Dec 09; 19(12).
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Sonic Hedgehog Signaling Pathway in Endothelial Progenitor Cell Biology for Vascular Medicine. Int J Mol Sci. 2018 Oct 05; 19(10).
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The Neuroprotective Roles of Sonic Hedgehog Signaling Pathway in Ischemic Stroke. Neurochem Res. 2018 Dec; 43(12):2199-2211.
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Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. J Clin Invest. 2018 10 01; 128(10):4343-4358.