"Sirtuin 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.
| Descriptor ID |
D056566
|
| MeSH Number(s) |
D08.811.277.087.520.200.650.600 D08.811.913.400.725.115.961.600 D12.776.476.900.600 D12.776.575.875
|
| Concept/Terms |
Sirtuin 3- Sirtuin 3
- Silent Mating Type Information Regulation 2 Homolog 3
|
Below are MeSH descriptors whose meaning is more general than "Sirtuin 3".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 3".
This graph shows the total number of publications written about "Sirtuin 3" by people in this website by year, and whether "Sirtuin 3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 5 | 2 | 7 |
| 2018 | 4 | 0 | 4 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sirtuin 3" by people in Profiles.
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Metformin combined with nelfinavir induces SIRT3/mROS-dependent autophagy in human cervical cancer cells and xenograft in nude mice. Eur J Pharmacol. 2019 Apr 05; 848:62-69.
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Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3. Int J Mol Sci. 2018 Aug 18; 19(8).
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SIRT3 restricts hepatitis B virus transcription and replication through epigenetic regulation of covalently closed circular DNA involving suppressor of variegation 3-9 homolog 1 and SET domain containing 1A histone methyltransferases. Hepatology. 2018 10; 68(4):1260-1276.
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Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy. Redox Biol. 2018 09; 18:229-243.
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The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts. J Thromb Thrombolysis. 2018 Jul; 46(1):102-112.
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Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function. Nat Commun. 2017 10 17; 8(1):983.
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Metformin and insulin impact on clinical outcome in patients with advanced hepatocellular carcinoma receiving sorafenib: Validation study and biological rationale. Eur J Cancer. 2017 11; 86:106-114.
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The sirtuin family members SIRT1, SIRT3 and SIRT6: Their role in vascular biology and atherogenesis. Atherosclerosis. 2017 10; 265:275-282.
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Melatonin protects against diabetic cardiomyopathy through Mst1/Sirt3 signaling. J Pineal Res. 2017 Sep; 63(2).
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SIRT3 functions as a tumor suppressor in hepatocellular carcinoma. Tumour Biol. 2017 Mar; 39(3):1010428317691178.