"Sirtuin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
| Descriptor ID |
D056564
|
| MeSH Number(s) |
D08.811.277.087.520.200.650.100 D12.776.476.900.100
|
| Concept/Terms |
Sirtuin 1- Sirtuin 1
- Silent Mating Type Information Regulation 2 Homolog 1
|
Below are MeSH descriptors whose meaning is more general than "Sirtuin 1".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 1".
This graph shows the total number of publications written about "Sirtuin 1" by people in this website by year, and whether "Sirtuin 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2016 | 2 | 2 | 4 |
| 2017 | 9 | 5 | 14 |
| 2018 | 12 | 5 | 17 |
| 2019 | 5 | 0 | 5 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sirtuin 1" by people in Profiles.
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Histone deficiency and accelerated replication stress in T cell aging. J Clin Invest. 2021 06 01; 131(11).
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The unbalanced p53/SIRT1 axis may impact lymphocyte homeostasis in COVID-19 patients. Int J Infect Dis. 2021 Apr; 105:49-53.
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COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity. Med Hypotheses. 2020 Nov; 144:110044.
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Irisin modulates genes associated with severe coronavirus disease (COVID-19) outcome in human subcutaneous adipocytes cell culture. Mol Cell Endocrinol. 2020 09 15; 515:110917.
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[Coronavirus disease (COVID-19) and sirtuins]. Rev Fac Cien Med Univ Nac Cordoba. 2020 06 16; 77(2):117-125.
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Hsa-miR-217 Inhibits the Proliferation, Migration, and Invasion in Non-small Cell Lung Cancer Cells Via Targeting SIRT1 and P53/KAI1 Signaling Balkan Med J. 2020 06 01; 37(1):208-214.
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Nicotinamide: Oversight of Metabolic Dysfunction Through SIRT1, mTOR, and Clock Genes. Curr Neurovasc Res. 2020; 17(5):765-783.
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A Yeast Suppressor Screen Used To Identify Mammalian SIRT1 as a Proviral Factor for Middle East Respiratory Syndrome Coronavirus Replication. J Virol. 2019 08 15; 93(16).
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Activation of liver x receptors prevents the spinal LTP induced by skin/muscle retraction in the thigh via SIRT1/NF-?b pathway. Neurochem Int. 2019 09; 128:106-114.
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Aloin Reduces HMGB1-Mediated Septic Responses and Improves Survival in Septic Mice by Activation of the SIRT1 and PI3K/Nrf2/HO-1 Signaling Axis. Am J Chin Med. 2019; 47(3):613-633.