Protein Tyrosine Phosphatase, Non-Receptor Type 11
"Protein Tyrosine Phosphatase, Non-Receptor Type 11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatases that contain two SRC HOMOLOGY DOMAINS. Mutations in the gene for protein tyrosine phosphatase, non-receptor type 11 are associated with NOONAN SYNDROME.
| Descriptor ID |
D054592
|
| MeSH Number(s) |
D08.811.277.352.650.775.300.800 D08.811.277.352.650.775.700.800 D12.644.360.585.800 D12.776.476.564.800 D12.776.476.800.800
|
| Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 11- Protein Tyrosine Phosphatase, Non-Receptor Type 11
- Protein Tyrosine Phosphatase, Non Receptor Type 11
- SHPTP2
- Phosphotyrosine Phosphatase Syp
- SHP-2 Protein-Tyrosine Phosphatase
- Protein Tyrosine Phosphatase PTP3
- Shp-2 Tyrosine Phosphatase
- Shp 2 Tyrosine Phosphatase
- Tyrosine Phosphatase, Shp-2
- SHP2 Phosphatase
- Phosphatase, SHP2
- Protein-Tyrosine-Phosphatase 2C
- Protein Tyrosine Phosphatase 2C
|
Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 11".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Hydrolases [D08.811.277]
- Esterases [D08.811.277.352]
- Phosphoric Monoester Hydrolases [D08.811.277.352.650]
- Protein Tyrosine Phosphatases [D08.811.277.352.650.775]
- Protein Tyrosine Phosphatases, Non-Receptor [D08.811.277.352.650.775.300]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D08.811.277.352.650.775.300.800]
- SH2 Domain-Containing Protein Tyrosine Phosphatases [D08.811.277.352.650.775.700]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D08.811.277.352.650.775.700.800]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Protein Tyrosine Phosphatases, Non-Receptor [D12.644.360.585]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D12.644.360.585.800]
- Proteins [D12.776]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Protein Tyrosine Phosphatases, Non-Receptor [D12.776.476.564]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D12.776.476.564.800]
- SH2 Domain-Containing Protein Tyrosine Phosphatases [D12.776.476.800]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D12.776.476.800.800]
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 11".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 11" by people in this website by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 11" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 11" by people in Profiles.
-
Role of lncRNA Morrbid in PTPN11(Shp2)E76K-driven juvenile myelomonocytic leukemia. Blood Adv. 2020 07 28; 4(14):3246-3251.
-
The tyrosine phosphatase SHP2 controls TGFß-induced STAT3 signaling to regulate fibroblast activation and fibrosis. Nat Commun. 2018 08 14; 9(1):3259.
-
Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Nat Med. 2018 07; 24(7):954-960.
-
Novel approaches to diagnosis and treatment of Juvenile Myelomonocytic Leukemia. Expert Rev Hematol. 2018 02; 11(2):129-143.
-
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia. Nat Commun. 2017 12 19; 8(1):2126.
-
Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-ß signaling. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10113-10118.
-
Shp2 Plays a Critical Role in IL-6-Induced EMT in Breast Cancer Cells. Int J Mol Sci. 2017 Feb 13; 18(2).
-
Sharing of a PTPN11 mutation by myelodysplastic bone marrow and a mature plasmacytoid dendritic cell proliferation provides evidence for their common myelomonocytic origin. Virchows Arch. 2017 04; 470(4):469-473.
-
Persistent activation of the D1R/Shp-2/Erk1/2 pathway in l-DOPA-induced dyskinesia in the 6-hydroxy-dopamine rat model of Parkinson's disease. Neurobiol Dis. 2013 Jun; 54:339-48.