Protein Tyrosine Phosphatase, Non-Receptor Type 2
"Protein Tyrosine Phosphatase, Non-Receptor Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.
| Descriptor ID |
D054578
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| MeSH Number(s) |
D08.811.277.352.650.775.300.200 D12.644.360.585.200 D12.776.476.564.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 2".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 2".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 2" by people in this website by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 2 | 0 | 2 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 2" by people in Profiles.
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Protein tyrosine phosphatase conjugated with a novel transdermal delivery peptide, astrotactin 1-derived peptide recombinant protein tyrosine phosphatase (AP-rPTP), alleviates both atopic dermatitis-like and psoriasis-like dermatitis. J Allergy Clin Immunol. 2018 01; 141(1):137-151.
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Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 Genes Are Associated with the Response to TNF Inhibitors in Patients with Rheumatoid Arthritis. PLoS One. 2017; 12(1):e0169956.