Matrix Metalloproteinase 13
"Matrix Metalloproteinase 13" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted matrix metalloproteinase that plays a physiological role in the degradation of extracellular matrix found in skeletal tissues. It is synthesized as an inactive precursor that is activated by the proteolytic cleavage of its N-terminal propeptide.
| Descriptor ID |
D053509
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| MeSH Number(s) |
D08.811.277.656.300.480.205.363 D08.811.277.656.300.480.525.700.550 D08.811.277.656.675.374.205.363 D08.811.277.656.675.374.525.700.550 D12.644.276.848.550 D12.776.467.836.550
|
| Concept/Terms |
Matrix Metalloproteinase 13- Matrix Metalloproteinase 13
- Metalloproteinase 13, Matrix
- Matrix Metalloproteinase-13
- Metalloproteinase-13, Matrix
- MMP13 Metalloproteinase
- Metalloproteinase, MMP13
- MMP-13 Metalloproteinase
- MMP 13 Metalloproteinase
- Metalloproteinase, MMP-13
- Collagenase-3
- Collagenase 3
|
Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinase 13".
Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinase 13".
This graph shows the total number of publications written about "Matrix Metalloproteinase 13" by people in this website by year, and whether "Matrix Metalloproteinase 13" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 3 | 4 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Matrix Metalloproteinase 13" by people in Profiles.
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Exenatide ameliorates inflammatory response in human rheumatoid arthritis fibroblast-like synoviocytes. IUBMB Life. 2019 07; 71(7):969-977.
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Follistatin-like protein 1 induction of matrix metalloproteinase 1, 3 and 13 gene expression in rheumatoid arthritis synoviocytes requires MAPK, JAK/STAT3 and NF-?B pathways. J Cell Physiol. 2018 01; 234(1):454-463.
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Downregulation of HS6ST2 by miR-23b-3p enhances matrix degradation through p38 MAPK pathway in osteoarthritis. Cell Death Dis. 2018 06 13; 9(6):699.
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Noncanonical Matrix Metalloprotease 1-Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis. Arterioscler Thromb Vasc Biol. 2018 06; 38(6):1368-1380.
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Resveratrol Alleviates Inflammatory Responses and Oxidative Stress in Rat Kidney Ischemia-Reperfusion Injury and H2O2-Induced NRK-52E Cells via the Nrf2/TLR4/NF-?B Pathway. Cell Physiol Biochem. 2018; 45(4):1677-1689.
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Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. J Med Chem. 2017 07 13; 60(13):5816-5825.
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Virtual High-Throughput Screening for Matrix Metalloproteinase Inhibitors. Methods Mol Biol. 2017; 1579:259-271.
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PEP-1-GRX-1 Modulates Matrix Metalloproteinase-13 and Nitric Oxide Expression of Human Articular Chondrocytes. Cell Physiol Biochem. 2017; 41(1):252-264.
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Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1ß-stimulated production of chemokines and matrix-degrading enzymes in vitro. PLoS One. 2014; 9(5):e96925.
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The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-?B nuclear protein translocation. Chem Biol Interact. 2012 Feb 05; 195(3):215-23.