"WT1 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Isoforms encoded by the WT1 Wilms tumor suppressor gene (GENES, WILMS TUMOR) and produced by alternative splicings. They are zinc finger-containing transcription factors involved in both transactivation and repression, and are critical for normal development and function of the urogenital tract.
| Descriptor ID |
D025721
|
| MeSH Number(s) |
D12.776.624.776.960
|
| Concept/Terms |
WT1 Proteins- WT1 Proteins
- Proteins, WT1
- WT1 Protein
- Protein, WT1
- WT1 Gene Product
- Gene Product, WT1
|
Below are MeSH descriptors whose meaning is more general than "WT1 Proteins".
Below are MeSH descriptors whose meaning is more specific than "WT1 Proteins".
This graph shows the total number of publications written about "WT1 Proteins" by people in this website by year, and whether "WT1 Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2017 | 4 | 1 | 5 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "WT1 Proteins" by people in Profiles.
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Generation of donor-derived Wilms tumor antigen 1-specific cytotoxic T lymphocytes with potent anti-leukemia activity for somatic cell therapy in children given haploidentical stem cell transplantation: a feasibility pre-clinical study. Cytotherapy. 2019 09; 21(9):958-972.
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Single-nephron proteomes connect morphology and function in proteinuric kidney disease. Kidney Int. 2018 06; 93(6):1308-1319.
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Polymorphisms in the Wilms Tumor Gene Are Associated With Interindividual Variations in Rubella Virus-Specific Cellular Immunity After Measles-Mumps-Rubella II Vaccination. J Infect Dis. 2018 01 30; 217(4):560-566.
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Napsin A and WT 1 are useful immunohistochemical markers for differentiating clear cell carcinoma ovary from high-grade serous carcinoma. APMIS. 2018 Jan; 126(1):45-55.
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Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia. Blood. 2017 10 12; 130(15):1713-1721.
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Heat shock protein 70/nitric oxide effect on stretched tubular epithelial cells linked to WT-1 cytoprotection during neonatal obstructive nephropathy. Int Urol Nephrol. 2017 Oct; 49(10):1875-1892.
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Wilms Tumor 1 gene expression levels improve risk stratification in AML patients. Results of a multicentre study within the Spanish Group for Molecular Biology in Haematology. Br J Haematol. 2018 05; 181(4):542-546.
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Safety and immunogenicity of neoadjuvant treatment using WT1-immunotherapeutic in combination with standard therapy in patients with WT1-positive Stage II/III breast cancer: a randomized Phase I study. Breast Cancer Res Treat. 2017 04; 162(3):479-488.
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The role of immunohistochemistry in the study of the newborn kidney. J Matern Fetal Neonatal Med. 2012 Oct; 25 Suppl 4:135-8.
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WT1 CpG islands methylation in human lung cancer: a pilot study. Biochem Biophys Res Commun. 2012 Sep 28; 426(3):306-9.