Adenomatous Polyposis Coli Protein
"Adenomatous Polyposis Coli Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.
| Descriptor ID |
D025601
|
| MeSH Number(s) |
D05.500.117.249 D12.776.220.040 D12.776.476.081.249 D12.776.624.776.010
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli Protein".
Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli Protein".
This graph shows the total number of publications written about "Adenomatous Polyposis Coli Protein" by people in this website by year, and whether "Adenomatous Polyposis Coli Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 3 | 4 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Adenomatous Polyposis Coli Protein" by people in Profiles.
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Variability in digestive and respiratory tract Ace2 expression is associated with the microbiome. PLoS One. 2021; 16(3):e0248730.
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Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3'-end. J Med Genet. 2020 05; 57(5):356-360.
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Targeted mutational analysis of inflammatory bowel disease-associated colorectal cancers. Hum Pathol. 2019 07; 89:44-50.
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Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Cell Host Microbe. 2018 Feb 14; 23(2):203-214.e5.
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Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing. BMC Med Genomics. 2017 05 19; 10(1):33.
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EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients. Gastroenterology. 2017 07; 153(1):178-190.e10.
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Clinical Activity of the ?-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis). J Clin Oncol. 2017 May 10; 35(14):1561-1569.
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The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein. Nat Commun. 2017 01 30; 8:14259.
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Breast cancer cells: Modulation by melatonin and the ubiquitin-proteasome system--a review. Mol Cell Endocrinol. 2015 Dec 05; 417:1-9.
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The roles of intrinsic disorder in orchestrating the Wnt-pathway. J Biomol Struct Dyn. 2012; 29(5):843-61.