Somatic Hypermutation, Immunoglobulin
"Somatic Hypermutation, Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A programmed mutation process whereby changes are introduced to the nucleotide sequence of immunoglobulin gene DNA during development.
| Descriptor ID |
D027041
|
| MeSH Number(s) |
G05.558.810 G12.500.780
|
| Concept/Terms |
Somatic Hypermutation, Immunoglobulin- Somatic Hypermutation, Immunoglobulin
- Hypermutation, Immunoglobulin Somatic
- Hypermutations, Immunoglobulin Somatic
- Immunoglobulin Somatic Hypermutations
- Somatic Hypermutations, Immunoglobulin
- Ig Somatic Hypermutation
- Immunoglobulin Somatic Hypermutation
- Hypermutation, Somatic, Immunoglobulin
- Somatic Hypermutation, Ig
- Hypermutation, Ig Somatic
- Hypermutations, Ig Somatic
- Ig Somatic Hypermutations
- Somatic Hypermutations, Ig
|
Below are MeSH descriptors whose meaning is more general than "Somatic Hypermutation, Immunoglobulin".
Below are MeSH descriptors whose meaning is more specific than "Somatic Hypermutation, Immunoglobulin".
This graph shows the total number of publications written about "Somatic Hypermutation, Immunoglobulin" by people in this website by year, and whether "Somatic Hypermutation, Immunoglobulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 2 | 2 | 4 |
| 2019 | 1 | 2 | 3 |
| 2020 | 1 | 3 | 4 |
| 2021 | 0 | 5 | 5 |
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Below are the most recent publications written about "Somatic Hypermutation, Immunoglobulin" by people in Profiles.
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Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2. Nature. 2021 08; 596(7872):417-422.
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SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2. Cell. 2021 07 22; 184(15):3936-3948.e10.
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Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants. Nature. 2021 07; 595(7866):278-282.
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IgV somatic mutation of human anti-SARS-CoV-2 monoclonal antibodies governs neutralization and breadth of reactivity. JCI Insight. 2021 05 10; 6(9).
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Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues. Science. 2021 05 14; 372(6543):738-741.
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Evolution of antibody immunity to SARS-CoV-2. Nature. 2021 03; 591(7851):639-644.
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Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation. Nat Commun. 2020 10 27; 11(1):5413.
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Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients. Cell. 2020 08 20; 182(4):843-854.e12.
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Broad neutralization of SARS-related viruses by human monoclonal antibodies. Science. 2020 08 07; 369(6504):731-736.
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Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation. Immunity. 2020 07 14; 53(1):98-105.e5.