"Dipeptidyl Peptidase 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.
| Descriptor ID |
D018819
|
| MeSH Number(s) |
D08.811.277.656.350.350.126 D08.811.277.656.959.250 D23.050.301.264.894.160 D23.101.100.894.160
|
| Concept/Terms |
Dipeptidyl Peptidase 4- Dipeptidyl Peptidase 4
- CD26 Antigen
- Antigen, CD26
- Antigens, CD26
- Adenosine Deaminase Complexing Protein 2
- Dipeptidyl-Peptidase IV
- Dipeptidyl Peptidase IV
- CD26 Antigens
|
Below are MeSH descriptors whose meaning is more general than "Dipeptidyl Peptidase 4".
Below are MeSH descriptors whose meaning is more specific than "Dipeptidyl Peptidase 4".
This graph shows the total number of publications written about "Dipeptidyl Peptidase 4" by people in this website by year, and whether "Dipeptidyl Peptidase 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2013 | 10 | 4 | 14 |
| 2014 | 4 | 3 | 7 |
| 2015 | 6 | 12 | 18 |
| 2016 | 6 | 7 | 13 |
| 2017 | 9 | 5 | 14 |
| 2018 | 14 | 3 | 17 |
| 2019 | 5 | 8 | 13 |
| 2020 | 9 | 12 | 21 |
| 2021 | 1 | 7 | 8 |
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Below are the most recent publications written about "Dipeptidyl Peptidase 4" by people in Profiles.
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Peptide Platform as a Powerful Tool in the Fight against COVID-19. Viruses. 2021 08 23; 13(8).
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Systemic DPP4/CD26 is associated with natural HIV-1 control: Implications for COVID-19 susceptibility. Clin Immunol. 2021 09; 230:108824.
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Dipeptidyl Peptidase-4 Inhibitors and COVID-19-Related Deaths among Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Observational Studies. Endocrinol Metab (Seoul). 2021 08; 36(4):904-908.
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Diabetic Nephropathy and COVID-19: The Potential Role of Immune Actors. Int J Mol Sci. 2021 Jul 21; 22(15).
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The lethal internal face of the coronaviruses: Kidney tropism of the SARS, MERS, and COVID19 viruses. IUBMB Life. 2021 08; 73(8):1005-1015.
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Does the SARS-CoV-2 Spike Protein Receptor Binding Domain Interact Effectively with the DPP4 (CD26) Receptor? A Molecular Docking Study. Int J Mol Sci. 2021 Jun 29; 22(13).
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Phenotypic and genetic characterization of MERS coronaviruses from Africa to understand their zoonotic potential. Proc Natl Acad Sci U S A. 2021 06 22; 118(25).
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Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity. Sci Adv. 2021 06; 7(25).
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Viral infiltration of pancreatic islets in patients with COVID-19. Nat Commun. 2021 06 10; 12(1):3534.
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Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 Survivors. Int J Mol Sci. 2021 Jun 07; 22(11).