Michael Farzan

InstitutionThe Scripps Research Institute
AddressJupiter
Florida
United States
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 11 Covid-19 publications, with a maximum of 2 publications in October 2020 and November 2020 and January 2021 and April 2021
    All Publications
    Bar chart showing 109 publications over 20 distinct years, with a maximum of 14 publications in 2006
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

    To see the data from both graphs as text, click here.
    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Janaka SK, Clark NM, Evans DT, Mou H, Farzan M, Connor JP. Predicting the efficacy of COVID-19 convalescent plasma donor units with the Lumit Dx anti-receptor binding domain assay. PLoS One. 2021; 16(7):e0253551. PMID: 34310603.
      Citations: 1     Fields:    Translation:HumansCells
    2. Guo Y, He W, Mou H, Zhang L, Chang J, Peng S, Ojha A, Tavora R, Parcells MS, Luo G, Li W, Zhong G, Choe H, Farzan M, Quinlan BD. An Engineered Receptor-Binding Domain Improves the Immunogenicity of Multivalent SARS-CoV-2 Vaccines. mBio. 2021 05 11; 12(3). PMID: 33975938.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    3. Choe H, Farzan M. How SARS-CoV-2 first adapted in humans. Science. 2021 04 30; 372(6541):466-467. PMID: 33926942.
      Citations: 7     Fields:    Translation:Humans
    4. Mou H, Quinlan BD, Peng H, Liu G, Guo Y, Peng S, Zhang L, Davis-Gardner ME, Gardner MR, Crynen G, DeVaux LB, Voo ZX, Bailey CC, Alpert MD, Rader C, Gack MU, Choe H, Farzan M. Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2. PLoS Pathog. 2021 04; 17(4):e1009501. PMID: 33836016.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    5. Ou T, Mou H, Zhang L, Ojha A, Choe H, Farzan M. Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2. PLoS Pathog. 2021 01; 17(1):e1009212. PMID: 33465165.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    6. Xiao T, Lu J, Zhang J, Johnson RI, McKay LGA, Storm N, Lavine CL, Peng H, Cai Y, Rits-Volloch S, Lu S, Quinlan BD, Farzan M, Seaman MS, Griffiths A, Chen B. A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent. Nat Struct Mol Biol. 2021 02; 28(2):202-209. PMID: 33432247.
      Citations: 18     Fields:    Translation:HumansCells
    7. Zhang L, Jackson CB, Mou H, Ojha A, Peng H, Quinlan BD, Rangarajan ES, Pan A, Vanderheiden A, Suthar MS, Li W, Izard T, Rader C, Farzan M, Choe H. SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity. Nat Commun. 2020 11 26; 11(1):6013. PMID: 33243994.
      Citations: 210     Fields:    Translation:HumansCellsPHPublic Health
    8. Jackson CB, Zhang L, Farzan M, Choe H. Functional importance of the D614G mutation in the SARS-CoV-2 spike protein. Biochem Biophys Res Commun. 2021 01 29; 538:108-115. PMID: 33220921.
      Citations: 13     Fields:    Translation:HumansCells
    9. Li Y, Wang H, Tang X, Fang S, Ma D, Du C, Wang Y, Pan H, Yao W, Zhang R, Zou X, Zheng J, Xu L, Farzan M, Zhong G. SARS-CoV-2 and Three Related Coronaviruses Utilize Multiple ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig. J Virol. 2020 10 27; 94(22). PMID: 32847856.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    10. Smith E, Davis-Gardner ME, Garcia-Ordonez RD, Nguyen TT, Hull M, Chen E, Baillargeon P, Scampavia L, Strutzenberg T, Griffin PR, Farzan M, Spicer TP. High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2. SLAS Discov. 2020 12; 25(10):1152-1161. PMID: 33043784.
      Citations: 10     Fields:    Translation:HumansCells
    11. Laczkó D, Hogan MJ, Toulmin SA, Hicks P, Lederer K, Gaudette BT, Castaño D, Amanat F, Muramatsu H, Oguin TH, Ojha A, Zhang L, Mu Z, Parks R, Manzoni TB, Roper B, Strohmeier S, Tombácz I, Arwood L, Nachbagauer R, Karikó K, Greenhouse J, Pessaint L, Porto M, Putman-Taylor T, Strasbaugh A, Campbell TA, Lin PJC, Tam YK, Sempowski GD, Farzan M, Choe H, Saunders KO, Haynes BF, Andersen H, Eisenlohr LC, Weissman D, Krammer F, Bates P, Allman D, Locci M, Pardi N. A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. Immunity. 2020 10 13; 53(4):724-732.e7. PMID: 32783919.
      Citations: 57     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    12. Poddar S, Hyde JL, Gorman MJ, Farzan M, Diamond MS. The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses. J Virol. 2016 10 01; 90(19):8780-94. PMID: 27440901.
      Citations: 38     Fields:    Translation:AnimalsCells
    13. Bailey CC, Zhong G, Huang IC, Farzan M. IFITM-Family Proteins: The Cell's First Line of Antiviral Defense. Annu Rev Virol. 2014 Nov 01; 1:261-283. PMID: 25599080.
      Citations: 178     Fields:    
    14. Jemielity S, Wang JJ, Chan YK, Ahmed AA, Li W, Monahan S, Bu X, Farzan M, Freeman GJ, Umetsu DT, Dekruyff RH, Choe H. TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog. 2013 Mar; 9(3):e1003232. PMID: 23555248.
      Citations: 133     Fields:    Translation:HumansAnimalsCells
    15. Demogines A, Farzan M, Sawyer SL. Evidence for ACE2-utilizing coronaviruses (CoVs) related to severe acute respiratory syndrome CoV in bats. J Virol. 2012 Jun; 86(11):6350-3. PMID: 22438550.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    16. Huang IC, Bailey CC, Weyer JL, Radoshitzky SR, Becker MM, Chiang JJ, Brass AL, Ahmed AA, Chi X, Dong L, Longobardi LE, Boltz D, Kuhn JH, Elledge SJ, Bavari S, Denison MR, Choe H, Farzan M. Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog. 2011 Jan 06; 7(1):e1001258. PMID: 21253575.
      Citations: 306     Fields:    Translation:HumansAnimalsCells
    17. Guo Y, Tisoncik J, McReynolds S, Farzan M, Prabhakar BS, Gallagher T, Rong L, Caffrey M. Identification of a new region of SARS-CoV S protein critical for viral entry. J Mol Biol. 2009 Dec 11; 394(4):600-5. PMID: 19853613.
      Citations: 21     Fields:    Translation:HumansCells
    18. Li W, Sui J, Huang IC, Kuhn JH, Radoshitzky SR, Marasco WA, Choe H, Farzan M. The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2. Virology. 2007 Oct 25; 367(2):367-74. PMID: 17631932.
      Citations: 75     Fields:    Translation:HumansCells
    19. Kuhn JH, Li W, Radoshitzky SR, Choe H, Farzan M. Severe acute respiratory syndrome coronavirus entry as a target of antiviral therapies. Antivir Ther. 2007; 12(4 Pt B):639-50. PMID: 17944271.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    20. Coughlin M, Lou G, Martinez O, Masterman SK, Olsen OA, Moksa AA, Farzan M, Babcook JS, Prabhakar BS. Generation and characterization of human monoclonal neutralizing antibodies with distinct binding and sequence features against SARS coronavirus using XenoMouse. Virology. 2007 Apr 25; 361(1):93-102. PMID: 17161858.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    21. Petit CM, Chouljenko VN, Iyer A, Colgrove R, Farzan M, Knipe DM, Kousoulas KG. Palmitoylation of the cysteine-rich endodomain of the SARS-coronavirus spike glycoprotein is important for spike-mediated cell fusion. Virology. 2007 Apr 10; 360(2):264-74. PMID: 17134730.
      Citations: 60     Fields:    Translation:AnimalsCells
    22. Hwang WC, Lin Y, Santelli E, Sui J, Jaroszewski L, Stec B, Farzan M, Marasco WA, Liddington RC. Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R. J Biol Chem. 2006 Nov 10; 281(45):34610-6. PMID: 16954221.
      Citations: 102     Fields:    Translation:HumansCells
    23. Li F, Berardi M, Li W, Farzan M, Dormitzer PR, Harrison SC. Conformational states of the severe acute respiratory syndrome coronavirus spike protein ectodomain. J Virol. 2006 Jul; 80(14):6794-800. PMID: 16809285.
      Citations: 60     Fields:    Translation:Cells
    24. He Y, Li J, Li W, Lustigman S, Farzan M, Jiang S. Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein. J Immunol. 2006 May 15; 176(10):6085-92. PMID: 16670317.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    25. Li W, Wong SK, Li F, Kuhn JH, Huang IC, Choe H, Farzan M. Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions. J Virol. 2006 May; 80(9):4211-9. PMID: 16611880.
      Citations: 129     Fields:    Translation:HumansAnimalsCells
    26. Zhang L, Zhang F, Yu W, He T, Yu J, Yi CE, Ba L, Li W, Farzan M, Chen Z, Yuen KY, Ho D. Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals. J Med Virol. 2006 Jan; 78(1):1-8. PMID: 16299724.
      Citations: 95     Fields:    Translation:HumansCells
    27. Li W, Choe H, Farzan M. Insights from the association of SARS-CoV S-protein with its receptor, ACE2. Adv Exp Med Biol. 2006; 581:209-18. PMID: 17037532.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    28. Li F, Li W, Farzan M, Harrison SC. Interactions between SARS coronavirus and its receptor. Adv Exp Med Biol. 2006; 581:229-34. PMID: 17037534.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    29. Huang IC, Bosch BJ, Li W, Farzan M, Rottier PM, Choe H. SARS-CoV, but not HCoV-NL63, utilizes cathepsins to infect cells: viral entry. Adv Exp Med Biol. 2006; 581:335-8. PMID: 17037556.
      Citations: 16     Fields:    Translation:HumansCells
    30. Jia HP, Look DC, Hickey M, Shi L, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB. Infection of human airway epithelia by SARS coronavirus is associated with ACE2 expression and localization. Adv Exp Med Biol. 2006; 581:479-84. PMID: 17037581.
      Citations: 13     Fields:    Translation:HumansCells
    31. Huang IC, Bosch BJ, Li F, Li W, Lee KH, Ghiran S, Vasilieva N, Dermody TS, Harrison SC, Dormitzer PR, Farzan M, Rottier PJ, Choe H. SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells. J Biol Chem. 2006 Feb 10; 281(6):3198-203. PMID: 16339146.
      Citations: 166     Fields:    Translation:HumansAnimalsCells
    32. Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol. 2005 Dec; 79(23):14614-21. PMID: 16282461.
      Citations: 341     Fields:    Translation:HumansCells
    33. Li F, Li W, Farzan M, Harrison SC. Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science. 2005 Sep 16; 309(5742):1864-8. PMID: 16166518.
      Citations: 822     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    34. Petit CM, Melancon JM, Chouljenko VN, Colgrove R, Farzan M, Knipe DM, Kousoulas KG. Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion. Virology. 2005 Oct 25; 341(2):215-30. PMID: 16099010.
      Citations: 32     Fields:    Translation:AnimalsCells
    35. Sui J, Li W, Roberts A, Matthews LJ, Murakami A, Vogel L, Wong SK, Subbarao K, Farzan M, Marasco WA. Evaluation of human monoclonal antibody 80R for immunoprophylaxis of severe acute respiratory syndrome by an animal study, epitope mapping, and analysis of spike variants. J Virol. 2005 May; 79(10):5900-6. PMID: 15857975.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    36. Li W, Zhang C, Sui J, Kuhn JH, Moore MJ, Luo S, Wong SK, Huang IC, Xu K, Vasilieva N, Murakami A, He Y, Marasco WA, Guan Y, Choe H, Farzan M. Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2. EMBO J. 2005 Apr 20; 24(8):1634-43. PMID: 15791205.
      Citations: 420     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    37. Chen Z, Zhang L, Qin C, Ba L, Yi CE, Zhang F, Wei Q, He T, Yu W, Yu J, Gao H, Tu X, Gettie A, Farzan M, Yuen KY, Ho DD. Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region. J Virol. 2005 Mar; 79(5):2678-88. PMID: 15708987.
      Citations: 103     Fields:    Translation:AnimalsCells
    38. He Y, Zhou Y, Liu S, Kou Z, Li W, Farzan M, Jiang S. Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine. Biochem Biophys Res Commun. 2004 Nov 12; 324(2):773-81. PMID: 15474494.
      Citations: 183     Fields:    Translation:HumansAnimalsCells
    39. Moore MJ, Dorfman T, Li W, Wong SK, Li Y, Kuhn JH, Coderre J, Vasilieva N, Han Z, Greenough TC, Farzan M, Choe H. Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2. J Virol. 2004 Oct; 78(19):10628-35. PMID: 15367630.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    40. Li W, Greenough TC, Moore MJ, Vasilieva N, Somasundaran M, Sullivan JL, Farzan M, Choe H. Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2. J Virol. 2004 Oct; 78(20):11429-33. PMID: 15452268.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    41. Sui J, Li W, Murakami A, Tamin A, Matthews LJ, Wong SK, Moore MJ, Tallarico AS, Olurinde M, Choe H, Anderson LJ, Bellini WJ, Farzan M, Marasco WA. Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2536-41. PMID: 14983044.
      Citations: 267     Fields:    Translation:HumansCells
    42. Wong SK, Li W, Moore MJ, Choe H, Farzan M. A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2. J Biol Chem. 2004 Jan 30; 279(5):3197-201. PMID: 14670965.
      Citations: 310     Fields:    Translation:HumansCells
    43. Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA, Somasundaran M, Sullivan JL, Luzuriaga K, Greenough TC, Choe H, Farzan M. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003 Nov 27; 426(6965):450-4. PMID: 14647384.
      Citations: 2230     Fields:    Translation:HumansAnimalsCells
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