"Coagulase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
| Descriptor ID |
D003030
|
| MeSH Number(s) |
D08.811.277.656.300.174 D12.776.097.181
|
| Concept/Terms |
Staphylococcal Clumping Factor- Staphylococcal Clumping Factor
- Clumping Factor, Staphylococcal
- Factor, Staphylococcal Clumping
- Clumping Factor (Staphylococcal)
|
Below are MeSH descriptors whose meaning is more general than "Coagulase".
Below are MeSH descriptors whose meaning is more specific than "Coagulase".
This graph shows the total number of publications written about "Coagulase" by people in this website by year, and whether "Coagulase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 3 | 4 | 7 |
| 2019 | 1 | 3 | 4 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Coagulase" by people in Profiles.
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Increased number of positive coagulase-negative staphylococci in blood cultures is partly explained by increased use of intra-arterial catheters in patients with COVID-19. J Hosp Infect. 2021 09; 115:126-127.
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Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves. Eur Heart J. 2019 10 14; 40(39):3248-3259.
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Prevalence of infective endocarditis in patients with positive blood cultures: a Danish nationwide study. Eur Heart J. 2019 10 14; 40(39):3237-3244.
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A short course of antibiotic treatment is safe after catheter withdrawal in catheter-related bloodstream infections due to coagulase-negative staphylococci. Eur J Clin Microbiol Infect Dis. 2019 May; 38(5):977-983.
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Coagulase-Negative Staphylococci Pathogenomics. Int J Mol Sci. 2019 Mar 11; 20(5).
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Genomic Analysis of Multiresistant Staphylococcus capitis Associated with Neonatal Sepsis. Antimicrob Agents Chemother. 2018 11; 62(11).
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Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial. JAMA. 2018 09 25; 320(12):1249-1258.
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Assessment of the Dual Role of Clumping Factor A in S. Aureus Adhesion to Endothelium in Absence and Presence of Plasma. Thromb Haemost. 2018 Jul; 118(7):1230-1241.
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Influence of subinhibitory concentrations of NH125 on biofilm formation & virulence factors of Staphylococcus aureus. Future Med Chem. 2018 06 01; 10(11):1319-1331.
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Targeting Coagulase Activity in Staphylococcus aureus Bacteraemia: A Randomized Controlled Single-Centre Trial of Staphylothrombin Inhibition. Thromb Haemost. 2018 05; 118(5):818-829.