"Botulinum Toxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
| Descriptor ID |
D001905
|
| MeSH Number(s) |
D08.811.277.656.300.480.153 D08.811.277.656.675.374.153 D12.776.097.156 D23.946.123.179
|
| Concept/Terms |
Botulinum Toxins- Botulinum Toxins
- Toxins, Botulinum
- Botulinum Toxin
- Toxin, Botulinum
- Clostridium botulinum Toxins
- Toxins, Clostridium botulinum
- Botulin
|
Below are MeSH descriptors whose meaning is more general than "Botulinum Toxins".
Below are MeSH descriptors whose meaning is more specific than "Botulinum Toxins".
This graph shows the total number of publications written about "Botulinum Toxins" by people in this website by year, and whether "Botulinum Toxins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 6 | 3 | 9 |
| 2018 | 2 | 1 | 3 |
| 2019 | 3 | 0 | 3 |
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Below are the most recent publications written about "Botulinum Toxins" by people in Profiles.
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Botulinum Toxin Services for Neurorehabiliation: Recommendations for Challenges and Opportunities during the COVID-19 Pandemic. Toxins (Basel). 2021 08 22; 13(8).
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Anatomical locations of the motor endplates of sartorius muscle for botulinum toxin injections in treatment of muscle spasticity. Surg Radiol Anat. 2021 Dec; 43(12):2025-2030.
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A video of best practice recommendations for making botulinum toxin therapy safe during the COVID-19 pandemic. Neurol Sci. 2021 Sep; 42(9):3937-3938.
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Nonsurgical cosmetic practice and COVID-19. Clin Exp Dermatol. 2021 10; 46(7):1319-1320.
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The effects of COVID-19 pandemic countermeasures on patients receiving botulinum toxin therapy and on their caregivers: a study from an Italian cohort. Neurol Sci. 2021 Aug; 42(8):3071-3077.
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Consensus recommendations for botulinum toxin injections in the spasticity management of children with cerebral palsy during COVID-19 outbreak Turk J Med Sci. 2021 04 30; 51(2):385-392.
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De novo design of modular and tunable protein biosensors. Nature. 2021 03; 591(7850):482-487.
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Impact of COVID-19 on neurological patients attending a botulinum toxin service. Neurol Sci. 2021 02; 42(2):433-435.
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Re Facial aesthetic injections in clinical practice: Pretreatment and post-treatment consensus recommendations to minimise adverse outcome Region-specific changes in line with the Covid-19 pandemic. Australas J Dermatol. 2020 Nov; 61(4):362-366.
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"Masking" our emotions: Botulinum toxin, facial expression, and well-being in the age of COVID-19. J Cosmet Dermatol. 2020 09; 19(9):2154-2160.