Ubiquitin-Protein Ligases
"Ubiquitin-Protein Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.
Descriptor ID |
D044767
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MeSH Number(s) |
D08.811.464.938.750
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Concept/Terms |
Ubiquitin-Protein Ligases- Ubiquitin-Protein Ligases
- Ligases, Ubiquitin-Protein
- Ubiquitin Protein Ligases
- E3 Ubiquitin Ligase
- Ligase, E3 Ubiquitin
- Ubiquitin Ligase, E3
- Ubiquitin-Protein Ligase E3
- Ligase E3, Ubiquitin-Protein
- Ubiquitin Protein Ligase E3
- Ubiquitin Ligase E3
- Ligase E3, Ubiquitin
- Ubiquitin-Protein Ligase
- Ligase, Ubiquitin-Protein
- Ubiquitin Protein Ligase
- E3 Ligase
- Ligase, E3
|
Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Protein Ligases".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Protein Ligases".
This graph shows the total number of publications written about "Ubiquitin-Protein Ligases" by people in this website by year, and whether "Ubiquitin-Protein Ligases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 2 | 3 | 5 |
2015 | 1 | 0 | 1 |
2016 | 4 | 0 | 4 |
2017 | 15 | 12 | 27 |
2018 | 18 | 17 | 35 |
2019 | 4 | 4 | 8 |
2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "Ubiquitin-Protein Ligases" by people in Profiles.
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Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1. Proc Natl Acad Sci U S A. 2021 09 14; 118(37).
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[Induced degradation of proteins by PROTACs and other strategies: towards promising drugs]. Biol Aujourdhui. 2021; 215(1-2):25-43.
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The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling. J Biol Chem. 2021 09; 297(3):101041.
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SARS-CoV-2 N Protein Targets TRIM25-Mediated RIG-I Activation to Suppress Innate Immunity. Viruses. 2021 07 23; 13(8).
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Epigenetic and transcriptional control of interferon-ß. J Exp Med. 2021 09 06; 218(9).
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The SARS-CoV-2 RNA interactome. Mol Cell. 2021 07 01; 81(13):2838-2850.e6.
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Inhibition of HECT E3 ligases as potential therapy for COVID-19. Cell Death Dis. 2021 03 24; 12(4):310.
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Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins. mBio. 2021 03 16; 12(2).
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SARS-CoV-2 Nucleocapsid Protein Targets RIG-I-Like Receptor Pathways to Inhibit the Induction of Interferon Response. Cells. 2021 03 02; 10(3).
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Identifying potential drug targets and candidate drugs for COVID-19: biological networks and structural modeling approaches. F1000Res. 2021; 10:127.