Tumor Necrosis Factor alpha-Induced Protein 3
"Tumor Necrosis Factor alpha-Induced Protein 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity.
Descriptor ID |
D000072598
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MeSH Number(s) |
D08.811.037.750.500 D08.811.277.656.300.887.750 D08.811.464.938.750.813 D12.644.360.950 D12.776.476.938
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tumor Necrosis Factor alpha-Induced Protein 3".
Below are MeSH descriptors whose meaning is more specific than "Tumor Necrosis Factor alpha-Induced Protein 3".
This graph shows the total number of publications written about "Tumor Necrosis Factor alpha-Induced Protein 3" by people in this website by year, and whether "Tumor Necrosis Factor alpha-Induced Protein 3" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2017 | 4 | 1 | 5 |
2018 | 5 | 3 | 8 |
2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Tumor Necrosis Factor alpha-Induced Protein 3" by people in Profiles.
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Gene signatures and potential therapeutic targets of Middle East respiratory syndrome coronavirus (MERS-CoV)-infected human lung adenocarcinoma epithelial cells. J Microbiol Immunol Infect. 2021 Oct; 54(5):845-857.
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TNF-a-induced protein 3 is a key player in childhood asthma development and environment-mediated protection. J Allergy Clin Immunol. 2019 12; 144(6):1684-1696.e12.
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Polymorphisms associated with anti-TNF drugs response in patients with psoriasis and psoriatic arthritis. J Eur Acad Dermatol Venereol. 2019 Apr; 33(4):e175-e177.
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A20 inhibits the release of inflammatory cytokines by suppressing the activation of the nuclear factor-kappa B pathway in osteoarthritic fibroblast-like synoviocytes. Biochem Biophys Res Commun. 2019 01 15; 508(3):877-881.
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Anti-inflammatory activity of the decoction of Forsythia suspensa (Thunb.) Vahl is related to Nrf2 and A20. J Ethnopharmacol. 2018 Dec 05; 227:97-104.
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Keratinocyte Expression of A20/TNFAIP3 Controls Skin Inflammation Associated with Atopic Dermatitis and Psoriasis. J Invest Dermatol. 2019 01; 139(1):135-145.
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Large deletion in 6q associated to A20 haploinsufficiency and thoracoabdominal heterotaxy. Ann Rheum Dis. 2018 11; 77(11):1697-1698.
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Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-?B. J Am Soc Nephrol. 2018 06; 29(6):1636-1648.
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Evaluation of the TLR negative regulatory network in CVID patients. Genes Immun. 2019 03; 20(3):198-206.
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Telomere Dysfunction Disturbs Macrophage Mitochondrial Metabolism and the NLRP3 Inflammasome through the PGC-1a/TNFAIP3 Axis. Cell Rep. 2018 03 27; 22(13):3493-3506.