Inhibitor of Apoptosis Proteins
"Inhibitor of Apoptosis Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.
| Descriptor ID |
D051034
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| MeSH Number(s) |
D08.811.464.938.750.210 D12.644.360.075.437 D12.776.476.075.437
|
| Concept/Terms |
Inhibitor of Apoptosis Proteins- Inhibitor of Apoptosis Proteins
- Apoptosis Proteins Inhibitor
- Inhibitor-Of-Apoptosis Protein
- Inhibitor Of Apoptosis Protein
- Baculoviral Inhibitor Of Apoptosis Repeat Proteins
- IAP Repeat Containing Proteins
- IAP Protein (Apoptosis)
Baculoviral IAP Repeat-Containing 2 Protein- Baculoviral IAP Repeat-Containing 2 Protein
- Baculoviral IAP Repeat Containing 2 Protein
- Cellular Inhibitor of Apoptosis 1 Protein
- IAP2 Protein
- c-IAP1 Protein
- cIAP1 Protein
- Inhibitor of Apoptosis 2 Protein
- BIRC2 Protein
- Baculoviral IAP Repeat Containing Protein 2
|
Below are MeSH descriptors whose meaning is more general than "Inhibitor of Apoptosis Proteins".
Below are MeSH descriptors whose meaning is more specific than "Inhibitor of Apoptosis Proteins".
This graph shows the total number of publications written about "Inhibitor of Apoptosis Proteins" by people in this website by year, and whether "Inhibitor of Apoptosis Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 2 | 5 | 7 |
| 2018 | 5 | 1 | 6 |
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Below are the most recent publications written about "Inhibitor of Apoptosis Proteins" by people in Profiles.
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Role of the NLRP3 inflammasome in cancer. Mol Cancer. 2018 11 17; 17(1):158.
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Inhibitor of apoptosis protein-like protein-2: A novel growth accelerator for breast cancer cells. Oncol Rep. 2018 Oct; 40(4):2047-2055.
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PLAUR Confers Resistance to Gefitinib Through EGFR/P-AKT/Survivin Signaling Pathway. Cell Physiol Biochem. 2018; 47(5):1909-1924.
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Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme. EBioMedicine. 2018 Jul; 33:49-56.
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Role of X-linked inhibitor of apoptosis (XIAP) in frozen and thawed dormant and normal-hatched murine blastocysts. Cryobiology. 2018 06; 82:112-117.
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Survivin-Based Treatment Strategies for Squamous Cell Carcinoma. Int J Mol Sci. 2018 Mar 24; 19(4).
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Survivin and autoimmunity; the ins and outs. Immunol Lett. 2018 01; 193:14-24.
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The long-term prognostic value of survivin expressing circulating tumor cells in patients with high-risk non-muscle invasive bladder cancer (NMIBC). J Cancer Res Clin Oncol. 2017 Oct; 143(10):1971-1976.
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EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients. Gastroenterology. 2017 07; 153(1):178-190.e10.
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Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ. Oncogene. 2017 08 10; 36(32):4573-4584.