"von Willebrand Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
| Descriptor ID |
D014841
|
| MeSH Number(s) |
D12.776.124.125.920 D23.119.985
|
| Concept/Terms |
von Willebrand Factor- von Willebrand Factor
- Factor VIIIR-Ag
- Factor VIIIR Ag
- Factor VIIIR-RCo
- Factor VIIIR RCo
- Ristocetin-Willebrand Factor
- Ristocetin Willebrand Factor
- von Willebrand Protein
- Factor VIII-Related Antigen
- Factor VIII Related Antigen
- Ristocetin Cofactor
|
Below are MeSH descriptors whose meaning is more general than "von Willebrand Factor".
Below are MeSH descriptors whose meaning is more specific than "von Willebrand Factor".
This graph shows the total number of publications written about "von Willebrand Factor" by people in this website by year, and whether "von Willebrand Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 32 | 13 | 45 |
| 2018 | 13 | 12 | 25 |
| 2019 | 7 | 5 | 12 |
| 2020 | 5 | 3 | 8 |
| 2021 | 10 | 8 | 18 |
| 2022 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "von Willebrand Factor" by people in Profiles.
-
Distinctive Biomarker Features in the Endotheliopathy of COVID-19 and Septic Syndromes. Shock. 2022 01 01; 57(1):95-105.
-
Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets. Blood. 2021 10 21; 138(16):1481-1489.
-
Persistent endotheliopathy in the pathogenesis of long COVID syndrome. J Thromb Haemost. 2021 10; 19(10):2546-2553.
-
Role of von Willebrand Factor in COVID-19 Associated Coagulopathy. J Appl Lab Med. 2021 09 01; 6(5):1305-1315.
-
COVID-19 and biomarkers of thrombosis: focus on von Willebrand factor and extracellular vesicles. J Thromb Thrombolysis. 2021 Nov; 52(4):1010-1019.
-
Imbalance of von Willebrand factor and ADAMTS13 axis is rather a biomarker of strong inflammation and endothelial damage than a cause of thrombotic process in critically ill COVID-19 patients. J Thromb Haemost. 2021 09; 19(9):2193-2198.
-
Biomarkers of endothelial dysfunction and outcomes in coronavirus disease 2019 (COVID-19) patients: A systematic review and meta-analysis. Microvasc Res. 2021 11; 138:104224.
-
COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects. Angiogenesis. 2021 11; 24(4):755-788.
-
ADAMTS13 regulation of VWF multimer distribution in severe COVID-19. J Thromb Haemost. 2021 08; 19(8):1914-1921.
-
Extracorporeal Membrane Oxygenation Induces Early Alterations in Coagulation and Fibrinolysis Profiles in COVID-19 Patients with Acute Respiratory Distress Syndrome. Thromb Haemost. 2021 Aug; 121(8):1031-1042.