Nucleocytoplasmic Transport Proteins
"Nucleocytoplasmic Transport Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins involved in the process of transporting molecules in and out the cell nucleus. Included here are: NUCLEOPORINS, which are membrane proteins that form the NUCLEAR PORE COMPLEX; KARYOPHERINS, which carry molecules through the nuclear pore complex; and proteins that play a direct role in the transport of karyopherin complexes through the nuclear pore complex.
Descriptor ID |
D029543
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MeSH Number(s) |
D12.776.157.530.750 D12.776.543.585.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleocytoplasmic Transport Proteins".
Below are MeSH descriptors whose meaning is more specific than "Nucleocytoplasmic Transport Proteins".
This graph shows the total number of publications written about "Nucleocytoplasmic Transport Proteins" by people in this website by year, and whether "Nucleocytoplasmic Transport Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2017 | 1 | 1 | 2 |
2019 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Nucleocytoplasmic Transport Proteins" by people in Profiles.
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How SARS-CoV-2 and Other Viruses Build an Invasion Route to Hijack the Host Nucleocytoplasmic Trafficking System. Cells. 2021 06 07; 10(6).
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SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98. mBio. 2021 04 13; 12(2).
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Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression. Sci Adv. 2021 02; 7(6).
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Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex. Biochem Biophys Res Commun. 2021 01 15; 536:59-66.
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SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28344-28354.
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Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations. J Chem Theory Comput. 2019 Oct 08; 15(10):5703-5715.
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AF119895 regulates NXF3 expression to promote migration and invasion of hepatocellular carcinoma through an interaction with miR-6508-3p. Exp Cell Res. 2018 02 01; 363(1):129-139.
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The mitotic checkpoint regulator RAE1 induces aggressive breast cancer cell phenotypes by mediating epithelial-mesenchymal transition. Sci Rep. 2017 02 09; 7:42256.
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A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export. Cell Host Microbe. 2016 Nov 09; 20(5):642-653.
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Activating receptor NKG2D targets RAE-1-expressing allogeneic neural precursor cells in a viral model of multiple sclerosis. Stem Cells. 2014 Oct; 32(10):2690-701.