Receptors, Aryl Hydrocarbon
"Receptors, Aryl Hydrocarbon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
| Descriptor ID |
D018336
|
| MeSH Number(s) |
D12.776.260.643.715 D12.776.826.209.715 D12.776.930.760
|
| Concept/Terms |
Receptors, Aryl Hydrocarbon- Receptors, Aryl Hydrocarbon
- Aryl Hydrocarbon Receptor
- Receptor, Aryl Hydrocarbon
- Aryl Hydrocarbon Receptors
- Dioxin Receptor
- Receptor, Dioxin
- Dioxin Receptors
- Receptors, Dioxin
- Polyaromatic Hydrocarbon Receptors
- Polyaromatic Hydrocarbon Receptor
- Receptor, Polyaromatic Hydrocarbon
- Receptors, Polyaromatic Hydrocarbon
- TCDD Receptor
- Receptor, TCDD
- Receptors, TCDD
- TCDD Receptors
- AH Receptor
- Receptor, AH
- AH Receptors
- Receptors, AH
- Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Aryl Hydrocarbon".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Aryl Hydrocarbon".
This graph shows the total number of publications written about "Receptors, Aryl Hydrocarbon" by people in this website by year, and whether "Receptors, Aryl Hydrocarbon" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 2 | 0 | 2 |
| 2017 | 5 | 0 | 5 |
| 2018 | 13 | 1 | 14 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Aryl Hydrocarbon" by people in Profiles.
-
AHR signaling is induced by infection with coronaviruses. Nat Commun. 2021 08 26; 12(1):5148.
-
Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal. Sci Rep. 2021 08 17; 11(1):16629.
-
Cigarette Smoke Stimulates SARS-CoV-2 Internalization by Activating AhR and Increasing ACE2 Expression in Human Gingival Epithelial Cells. Int J Mol Sci. 2021 Jul 18; 22(14).
-
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction. Biochem Pharmacol. 2021 06; 188:114564.
-
ACE2 expression is regulated by AhR in SARS-CoV-2-infected macaques. Cell Mol Immunol. 2021 05; 18(5):1308-1310.
-
Low risk of the TMPRSS2 inhibitor camostat mesylate and its metabolite GBPA to act as perpetrators of drug-drug interactions. Chem Biol Interact. 2021 Apr 01; 338:109428.
-
Tryptophan Metabolites and Aryl Hydrocarbon Receptor in Severe Acute Respiratory Syndrome, Coronavirus-2 (SARS-CoV-2) Pathophysiology. Int J Mol Sci. 2021 Feb 05; 22(4).
-
SARS-CoV-2-induced lung pathology: AHR as a candidate therapeutic target. Cell Res. 2021 01; 31(1):1-2.
-
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19. Cell Res. 2020 12; 30(12):1078-1087.
-
Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide. Biosci Rep. 2020 10 30; 40(10).