Heterogeneous Nuclear Ribonucleoprotein A1
"Heterogeneous Nuclear Ribonucleoprotein A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous ribonucleoprotein that contains an RNA-BINDING MOTIF and has poly(ADP)ribose-binding capability. It functions in the packaging of pre-mRNA into hnRNP particles for export to the cytoplasm and may play a role in RNA SPLICING site selection.
| Descriptor ID |
D000076245
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| MeSH Number(s) |
D12.776.157.687.462 D12.776.157.725.813.750.100.500 D12.776.260.735.500.500 D12.776.660.235.700.500.500 D12.776.664.962.813.750.100.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Heterogeneous Nuclear Ribonucleoprotein A1".
Below are MeSH descriptors whose meaning is more specific than "Heterogeneous Nuclear Ribonucleoprotein A1".
This graph shows the total number of publications written about "Heterogeneous Nuclear Ribonucleoprotein A1" by people in this website by year, and whether "Heterogeneous Nuclear Ribonucleoprotein A1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heterogeneous Nuclear Ribonucleoprotein A1" by people in Profiles.
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Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex. Biochem Biophys Res Commun. 2021 01 15; 536:59-66.
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Cellular hnRNP A1 Interacts with Nucleocapsid Protein of Porcine Epidemic Diarrhea Virus and Impairs Viral Replication. Viruses. 2018 03 13; 10(3).
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High expression of hnRNPA1 promotes cell invasion by inducing EMT in gastric cancer. Oncol Rep. 2018 Apr; 39(4):1693-1701.
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Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Acta Crystallogr F Struct Biol Commun. 2017 04 01; 73(Pt 4):209-214.
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The nucleocapsid protein of SARS coronavirus has a high binding affinity to the human cellular heterogeneous nuclear ribonucleoprotein A1. FEBS Lett. 2005 May 09; 579(12):2623-8.
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Multiple type A/B heterogeneous nuclear ribonucleoproteins (hnRNPs) can replace hnRNP A1 in mouse hepatitis virus RNA synthesis. J Virol. 2003 Oct; 77(19):10584-93.
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Heterogeneous nuclear ribonucleoprotein a1 binds to the 3'-untranslated region and mediates potential 5'-3'-end cross talks of mouse hepatitis virus RNA. J Virol. 2001 Jun; 75(11):5009-17.
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Evaluation of the role of heterogeneous nuclear ribonucleoprotein A1 as a host factor in murine coronavirus discontinuous transcription and genome replication. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2717-22.
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Regulation of mouse hepatitis virus RNA synthesis by heterogeneous nuclear ribonucleoprotein A1. Adv Exp Med Biol. 2001; 494:429-36.
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Role of hnRNP A1 in coronavirus RNA synthesis. Adv Exp Med Biol. 2001; 494:437-46.