"Ku Autoantigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.
| Descriptor ID |
D000072200
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| MeSH Number(s) |
D08.811.277.040.025.159.155 D08.811.399.340.155 D12.776.157.687.493 D12.776.260.525 D12.776.660.625.625 D12.776.660.720.493 D23.050.290.625
|
| Concept/Terms |
Ku Autoantigen- Ku Autoantigen
- Autoantigen, Ku
- Ku Heterodimer
- Heterodimer, Ku
- Ku Protein
- Ku Antigen
- Antigen, Ku
- G22P1 Antigen
- Antigen, G22P1
Ku80 Antigen- Ku80 Antigen
- Antigen, Ku80
- Ku Autoantigen, 80 kDa
- XRCC5 Protein
- X-ray Repair Cross-Complementing Protein 5
- X ray Repair Cross Complementing Protein 5
Ku70 Antigen- Ku70 Antigen
- Antigen, Ku70
- Ku Autoantigen, 70 kDa
- XRCC6 Protein
- X-ray Repair Cross-Complementing Protein 6
- X ray Repair Cross Complementing Protein 6
|
Below are MeSH descriptors whose meaning is more general than "Ku Autoantigen".
Below are MeSH descriptors whose meaning is more specific than "Ku Autoantigen".
This graph shows the total number of publications written about "Ku Autoantigen" by people in this website by year, and whether "Ku Autoantigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ku Autoantigen" by people in Profiles.
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Case report of COVID-19 in an elderly patient: could SARS-CoV2 trigger myositis? Eur Rev Med Pharmacol Sci. 2020 11; 24(22):11960-11963.
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Yeast-based assays for characterization of the functional effects of single nucleotide polymorphisms in human DNA repair genes. PLoS One. 2018; 13(3):e0193823.
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STING is an essential mediator of the Ku70-mediated production of IFN-?1 in response to exogenous DNA. Sci Signal. 2017 Jul 18; 10(488).
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HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response. Mol Cell. 2017 Aug 03; 67(3):387-399.e5.
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DNA-PK facilitates piggyBac transposition by promoting paired-end complex formation. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):7408-7413.
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HPV and systemic lupus erythematosus: a mosaic of potential crossreactions. Immunol Res. 2017 04; 65(2):564-571.
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Deacetylation of Ku70 by SIRT6 attenuates Bax-mediated apoptosis in hepatocellular carcinoma. Biochem Biophys Res Commun. 2017 04 15; 485(4):713-719.
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Ku70, Ku80, and sClusterin: A Cluster of Predicting Factors for Response to Neoadjuvant Chemoradiation Therapy in Patients With Locally Advanced Rectal Cancer. Int J Radiat Oncol Biol Phys. 2017 02 01; 97(2):381-388.