"Point Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mutation caused by the substitution of one nucleotide for another. This results in the DNA molecule having a change in a single base pair.
| Descriptor ID |
D017354
|
| MeSH Number(s) |
G05.365.590.675
|
| Concept/Terms |
Point Mutation- Point Mutation
- Mutation, Point
- Mutations, Point
- Point Mutations
|
Below are MeSH descriptors whose meaning is more general than "Point Mutation".
Below are MeSH descriptors whose meaning is more specific than "Point Mutation".
This graph shows the total number of publications written about "Point Mutation" by people in this website by year, and whether "Point Mutation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 5 | 5 |
| 2006 | 1 | 4 | 5 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 2 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 2 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 11 | 12 | 23 |
| 2018 | 4 | 13 | 17 |
| 2019 | 3 | 7 | 10 |
| 2020 | 0 | 2 | 2 |
| 2021 | 2 | 6 | 8 |
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Below are the most recent publications written about "Point Mutation" by people in Profiles.
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A real-time and high-throughput neutralization test based on SARS-CoV-2 pseudovirus containing monomeric infrared fluorescent protein as reporter. Emerg Microbes Infect. 2021 Dec; 10(1):894-904.
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Isolation of SARS-CoV-2 strains carrying a nucleotide mutation, leading to a stop codon in the ORF 6 protein. Emerg Microbes Infect. 2021 Dec; 10(1):252-255.
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Cerebral venous thrombosis and myeloproliferative neoplasms: A three-center study of 74 consecutive cases. Am J Hematol. 2021 12 01; 96(12):1580-1586.
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Interface-based design of the favipiravir-binding site in SARS-CoV-2 RNA-dependent RNA polymerase reveals mutations conferring resistance to chain termination. FEBS Lett. 2021 09; 595(18):2366-2382.
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SELP Asp603Asn and severe thrombosis in COVID-19 males. J Hematol Oncol. 2021 08 16; 14(1):123.
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Deep geometric representations for modeling effects of mutations on protein-protein binding affinity. PLoS Comput Biol. 2021 08; 17(8):e1009284.
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Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant. Sci Rep. 2021 07 01; 11(1):13705.
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Activation of NF-?B and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2. Sci Rep. 2021 06 29; 11(1):13464.
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Remdesivir MD Simulations Suggest a More Favourable Binding to SARS-CoV-2 RNA Dependent RNA Polymerase Mutant P323L Than Wild-Type. Biomolecules. 2021 06 22; 11(7).
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Decoding molnupiravir-induced mutagenesis in SARS-CoV-2. J Biol Chem. 2021 07; 297(1):100867.