"Germ-Line Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not.
| Descriptor ID |
D018095
|
| MeSH Number(s) |
G05.365.590.350
|
| Concept/Terms |
Germ-Line Mutation- Germ-Line Mutation
- Germ Line Mutation
- Germline Mutation
- Germline Mutations
- Mutation, Germline
- Mutations, Germline
- Mutation, Germ-Line
- Germ-Line Mutations
- Mutation, Germ Line
- Mutations, Germ-Line
|
Below are MeSH descriptors whose meaning is more general than "Germ-Line Mutation".
Below are MeSH descriptors whose meaning is more specific than "Germ-Line Mutation".
This graph shows the total number of publications written about "Germ-Line Mutation" by people in this website by year, and whether "Germ-Line Mutation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 16 | 13 | 29 |
| 2018 | 11 | 14 | 25 |
| 2019 | 6 | 12 | 18 |
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Below are the most recent publications written about "Germ-Line Mutation" by people in Profiles.
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Editorial: Do not lose focus on myeloid biology in the era of COVID-19. Curr Opin Hematol. 2021 03 01; 28(2):71-72.
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Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies. J Immunother Cancer. 2019 10 22; 7(1):272.
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Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3'-end. J Med Genet. 2020 05; 57(5):356-360.
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BAP1 Tumour Predisposition Syndrome: A New Mutation in One Family. Acta Derm Venereol. 2019 10 01; 99(11):1045-1046.
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Familial lobular breast cancer: Is testing for germline CDH1 mutations necessary? Eur J Surg Oncol. 2019 Oct; 45(10):1760-1761.
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Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study. J Clin Oncol. 2019 09 01; 37(25):2246-2256.
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Pneumothorax and lung cysts: a family affair. Lancet. 2019 06 29; 393(10191):2635.
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Prognostic factors value of germline and somatic brca in patients undergoing surgery for recurrent ovarian cancer with liver metastases. Eur J Surg Oncol. 2019 Nov; 45(11):2096-2102.
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Melorheostosis and Osteopoikilosis Clinical and Molecular Description of an Italian Case Series. Calcif Tissue Int. 2019 Aug; 105(2):215-221.
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Positive/retained SDHB immunostaining in renal cell carcinomas associated to germline SDHB-deficiency: case report. Diagn Pathol. 2019 May 15; 14(1):42.