"Frameshift Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby causing an alteration in the READING FRAMES of the entire coding sequence downstream of the mutation. These mutations may be induced by certain types of MUTAGENS or may occur spontaneously.
| Descriptor ID |
D016368
|
| MeSH Number(s) |
G05.365.590.265
|
| Concept/Terms |
Frameshift Mutation- Frameshift Mutation
- Frameshift Mutations
- Mutations, Frameshift
- Out-of-Frame Mutation
- Mutation, Out-of-Frame
- Mutations, Out-of-Frame
- Out of Frame Mutation
- Out-of-Frame Mutations
- Frame Shift Mutation
- Frame Shift Mutations
- Mutation, Frame Shift
- Mutations, Frame Shift
- Mutation, Frameshift
Out-of-Frame Insertion- Out-of-Frame Insertion
- Insertion, Out-of-Frame
- Insertions, Out-of-Frame
- Out of Frame Insertion
- Out-of-Frame Insertions
Out-of-Frame Deletion- Out-of-Frame Deletion
- Deletion, Out-of-Frame
- Deletions, Out-of-Frame
- Out of Frame Deletion
- Out-of-Frame Deletions
|
Below are MeSH descriptors whose meaning is more general than "Frameshift Mutation".
Below are MeSH descriptors whose meaning is more specific than "Frameshift Mutation".
This graph shows the total number of publications written about "Frameshift Mutation" by people in this website by year, and whether "Frameshift Mutation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 2 | 5 | 7 |
| 2018 | 2 | 7 | 9 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 2 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Frameshift Mutation" by people in Profiles.
-
Characterization of SARS-CoV-2 ORF6 deletion variants detected in a nosocomial cluster during routine genomic surveillance, Lyon, France. Emerg Microbes Infect. 2021 Dec; 10(1):167-177.
-
Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nat Struct Mol Biol. 2021 09; 28(9):747-754.
-
Structural dynamics of single SARS-CoV-2 pseudoknot molecules reveal topologically distinct conformers. Nat Commun. 2021 08 06; 12(1):4749.
-
Genome sequencing of SARS-CoV-2 in a cohort of Egyptian patients revealed mutation hotspots that are related to clinical outcomes. Biochim Biophys Acta Mol Basis Dis. 2021 08 01; 1867(8):166154.
-
Effect of COVID-19 on anakinra-induced remission in homozygous STX11 hemophagocytosis lymphohistiocytosis. Pediatr Blood Cancer. 2021 06; 68(6):e28897.
-
Genomic surveillance of SARS-CoV-2 in Thailand reveals mixed imported populations, a local lineage expansion and a virus with truncated ORF7a. Virus Res. 2021 01 15; 292:198233.
-
Variant analysis of the first Lebanese SARS-CoV-2 isolates. Genomics. 2021 01; 113(1 Pt 2):892-895.
-
ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population. Eur J Hum Genet. 2020 11; 28(11):1602-1614.
-
A novel mutation causes Hermansky-Pudlak syndrome type 4 with pulmonary fibrosis in 2 siblings from China. Medicine (Baltimore). 2019 Aug; 98(33):e16899.
-
Long-Term Outcome of WHIM Syndrome in 18 Patients: High Risk of Lung Disease and HPV-Related Malignancies. J Allergy Clin Immunol Pract. 2019 May - Jun; 7(5):1568-1577.