"Interleukin-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.
| Descriptor ID |
D015850
|
| MeSH Number(s) |
D12.644.276.374.465.224 D12.776.467.374.465.202 D23.529.374.465.224
|
| Concept/Terms |
Interleukin-6- Interleukin-6
- Interleukin 6
- IL6
- B-Cell Stimulatory Factor 2
- B-Cell Stimulatory Factor-2
- Differentiation Factor-2, B-Cell
- Differentiation Factor 2, B Cell
- B-Cell Differentiation Factor-2
- B Cell Differentiation Factor 2
- BSF-2
- Hybridoma Growth Factor
- Growth Factor, Hybridoma
- IFN-beta 2
- Plasmacytoma Growth Factor
- Growth Factor, Plasmacytoma
- Hepatocyte-Stimulating Factor
- Hepatocyte Stimulating Factor
- MGI-2
- Myeloid Differentiation-Inducing Protein
- Differentiation-Inducing Protein, Myeloid
- Myeloid Differentiation Inducing Protein
- B-Cell Differentiation Factor
- B Cell Differentiation Factor
- Differentiation Factor, B-Cell
- Differentiation Factor, B Cell
- IL-6
- Interferon beta-2
- Interferon beta 2
- beta-2, Interferon
- B Cell Stimulatory Factor-2
- B Cell Stimulatory Factor 2
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-6".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-6".
This graph shows the total number of publications written about "Interleukin-6" by people in this website by year, and whether "Interleukin-6" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 3 | 0 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 3 | 5 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 6 | 7 |
| 2009 | 2 | 4 | 6 |
| 2010 | 3 | 7 | 10 |
| 2011 | 3 | 3 | 6 |
| 2012 | 1 | 7 | 8 |
| 2013 | 0 | 3 | 3 |
| 2014 | 2 | 10 | 12 |
| 2015 | 2 | 4 | 6 |
| 2016 | 7 | 8 | 15 |
| 2017 | 50 | 98 | 148 |
| 2018 | 35 | 76 | 111 |
| 2019 | 16 | 25 | 41 |
| 2020 | 69 | 147 | 216 |
| 2021 | 44 | 68 | 112 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-6" by people in Profiles.
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Biomarkers for Prognosis and Treatment Response in COVID-19 Patients. Ann Lab Med. 2021 Nov 01; 41(6):540-548.
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Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome in Children With Shock. Crit Care Med. 2021 11 01; 49(11):e1151-e1156.
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IL-6 Inhibition Reduces Neuronal Injury in a Murine Model of Ventilator-induced Lung Injury. Am J Respir Cell Mol Biol. 2021 10; 65(4):403-412.
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Profound Treg perturbations correlate with COVID-19 severity. Proc Natl Acad Sci U S A. 2021 09 14; 118(37).
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Guillain-Barré syndrome is immunogenic in SARS-CoV-2 infected. J Med Virol. 2022 01; 94(1):22-23.
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Elements of Th1/Th2 response and disease severity in COVID-19 patients: A short report. J Med Virol. 2022 01; 94(1):404-406.
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Repurposing Methotrexate in Dampening SARS-CoV2-S1-Mediated IL6 Expression: Lessons Learnt from Lung Cancer. Inflammation. 2022 Feb; 45(1):172-179.
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Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice. FASEB J. 2021 09; 35(9):e21801.
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Daily monitoring of viral load measured as SARS-CoV-2 antigen and RNA in blood, IL-6, CRP and complement C3d predicts outcome in patients hospitalized with COVID-19. Clin Chem Lab Med. 2021 Nov 25; 59(12):1988-1997.
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Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID-19. J Med Virol. 2022 01; 94(1):154-160.