"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
|
| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
|
| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 3 | 3 |
| 2010 | 1 | 2 | 3 |
| 2011 | 4 | 1 | 5 |
| 2012 | 0 | 2 | 2 |
| 2013 | 3 | 3 | 6 |
| 2014 | 1 | 2 | 3 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 4 | 6 |
| 2017 | 29 | 44 | 73 |
| 2018 | 20 | 41 | 61 |
| 2019 | 4 | 13 | 17 |
| 2020 | 6 | 21 | 27 |
| 2021 | 4 | 12 | 16 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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An Alternative "Trojan Horse" Hypothesis for COVID-19: Immune Deficiency of IL-10 and SARS-CoV-2 Biology. Endocr Metab Immune Disord Drug Targets. 2022; 22(1):1-5.
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Clinical and inflammatory features based machine learning model for fatal risk prediction of hospitalized COVID-19 patients: results from a retrospective cohort study. Ann Med. 2021 12; 53(1):257-266.
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Elements of Th1/Th2 response and disease severity in COVID-19 patients: A short report. J Med Virol. 2022 01; 94(1):404-406.
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Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice. FASEB J. 2021 09; 35(9):e21801.
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Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID-19. J Med Virol. 2022 01; 94(1):154-160.
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Suppressive Monocytes Impair MAIT Cells Response via IL-10 in Patients with Severe COVID-19. J Immunol. 2021 10 01; 207(7):1848-1856.
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Elevated Rates of Indeterminate Results on QuantiFERON-TB Gold Plus in COVID-19 Patients. J Clin Microbiol. 2021 09 20; 59(10):e0141421.
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Changes of serum IL-10, IL-1ß, IL-6, MCP-1, TNF-a, IP-10 and IL-4 in COVID-19 patients. Int J Clin Pract. 2021 Sep; 75(9):e14462.
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Elevated Interleukin-10 Levels in COVID-19: Potentiation of Pro-Inflammatory Responses or Impaired Anti-Inflammatory Action? Front Immunol. 2021; 12:677008.
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Chronic Immune Activation and CD4+ T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy. Front Immunol. 2021; 12:693269.