"Amphiregulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autocrine growth factor and mitogen for a broad range of target cells including EPITHELIAL CELLS; FIBROBLASTS and immune cells. It occurs as a membrane-bound protein that can be cleaved to release an active secreted form.
| Descriptor ID |
D066258
|
| MeSH Number(s) |
D12.644.276.382.249 D12.776.467.382.249 D12.776.543.029 D23.529.382.249
|
| Concept/Terms |
Amphiregulin- Amphiregulin
- Schwannoma-derived Growth Factor
- Schwannoma derived Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Amphiregulin".
Below are MeSH descriptors whose meaning is more specific than "Amphiregulin".
This graph shows the total number of publications written about "Amphiregulin" by people in this website by year, and whether "Amphiregulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amphiregulin" by people in Profiles.
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Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021 06 08; 54(6):1186-1199.e7.
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The Epidermal Growth Factor Receptor Ligand Amphiregulin Protects From Cholestatic Liver Injury and Regulates Bile Acids Synthesis. Hepatology. 2019 04; 69(4):1632-1647.
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Production of amphiregulin and recovery from influenza is greater in males than females. Biol Sex Differ. 2018 07 17; 9(1):24.
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Overactive Epidermal Growth Factor Receptor Signaling Leads to Increased Fibrosis after Severe Acute Respiratory Syndrome Coronavirus Infection. J Virol. 2017 06 15; 91(12).