"Utrophin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomally-encoded 376-kDa cytoskeletal protein that is similar in structure and function to DYSTROPHIN. It is a ubiquitously-expressed protein that plays a role in anchoring the CYTOSKELETON to the PLASMA MEMBRANE.
| Descriptor ID |
D049411
|
| MeSH Number(s) |
D12.776.220.987 D12.776.543.985
|
| Concept/Terms |
Utrophin- Utrophin
- UTRN Protein
- Dystrophin-Related Protein
- Dystrophin Related Protein
- Dystrophin-Related Protein 1
- Dystrophin Related Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Utrophin".
Below are MeSH descriptors whose meaning is more specific than "Utrophin".
This graph shows the total number of publications written about "Utrophin" by people in this website by year, and whether "Utrophin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Utrophin" by people in Profiles.
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Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice. Biochim Biophys Acta Mol Basis Dis. 2018 Apr; 1864(4 Pt A):1172-1182.
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Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice. Eur J Hum Genet. 2017 12; 25(12):1388-1396.